The purpose of this literature review is to provide relevant research results on the efficiency and validity of the platelet-rich plasma in various fields of medicine as well as to cover some unresolved issues and problems in this area. If one searches the keywords such as «platelet-rich plasma», «safety», «effects» in the Scopus and PubMed databases, 590 publications will be found over the past 5 years, most of which are in the field of orthopedics, gynecology and dermatology.

Autologous plasma enriched with platelets is widely used today in various fields of medicine. The platelet-rich plasma is so widely used because it releases numerous chemokines, cytokines, and growth factors that stimulate angiogenesis, extracellular matrix remodeling, and cell differentiation and proliferation. Numerous studies have shown positive local effects of the platelet-rich plasma: earlier vascularization, epithelialization, remodeling and tissue regeneration. However, current studies on the clinical efficiency of the platelet-rich plasma are not conclusive and homogeneous. The heterogeneity of the platelet-rich plasma specimens (different preparation methods, various concentrations of platelets and growth factors, the influence of age, sex, concomitant pathology of the patient) complicates the interpretation of the existing literature and limits the ability to give definitive recommendations on the clinical efficiency of the platelet-rich plasma. Presently, there is no comprehensive standard algorithm for the platelet-rich plasma preparation as well as no definite criteria for establishing indications for this procedure. The following issues remain unresolved: finding an effective method to prepare the platelet-rich plasma, determining the optimal concentration of platelets and growth factors, having insufficient knowledge about all molecular mechanisms of the platelet-rich plasma to promote tissue regeneration and systemic reactions to the introduction of the platelet-rich plasma. Further research is required to address all the issues raised.

The aim of this review is to study international experience and conduct a literature review on navigational and vaccination literacy in health. A review analysis of scientific publications dedicated to navigational and vaccination health literacy was conducted. Data collection was carried out using the PubMed, Web of Science, Cochrane Database of Systematic Reviews, and Scopus databases, as well as some medical journals. The selection criteria included the use of keywords (navigational health literacy, vaccination health literacy, health literacy), free access to the full text, and a time frame from 2000 to 2023. A total of 176 studies were analyzed, of which 83 were selected.

Navigational and vaccination health literacy are shaped by socio-demographic and economic factors, education level, information accessibility, and the organization of healthcare services. Navigational health literacy depends on the structure of medical institutions, the convenience of appointment scheduling, and digital skills. Vaccination health literacy is determined by an understanding of vaccination principles, trust in healthcare providers, and the ability to critically evaluate information. Key barriers include misinformation, fear of complications, and anti-vaccination attitudes. Risk perception plays a crucial role in vaccination decision-making, especially among parents and older adults.

Navigational and vaccination health literacy play a crucial role in the accessibility of medical services and successful immunization. Analysis of studies has shown that the organization of medical spaces, accessibility of information, and trust in vaccination influence patient satisfaction and behavior. The main barriers include informational and technological challenges, as well as anti-vaccination sentiments. Enhancing health literacy and optimizing services can improve vaccination rates and strengthen public health.

The causative agent of varicella virus is widespread. In children, especially with a complicated premorbid background, there is a high incidence of severe forms and complications. Widespread use of specific prophylaxis is necessary.

According to WHO estimates, 4.2 million registered cases of severe complications of chickenpox resulted in 4,200 deaths. Severe course of varicella virus, addition of complications and mortality are typical for newborns and individuals with impaired immune system. The following complications were identified in deceased patients with varicella virus: bacterial (55%), pneumonia (54%), hemorrhagic (41%), from the central nervous system (33%).

The genetic diversity of causative agent of varicella virus plays a key role in its pathogenicity, epidemiology and response to vaccination. Despite successful vaccination programs, the virus continues to circulate in the population, which emphasizes the need for a deep understanding of its genetic diversity. Genetic diversity of varicella-zoster viruses may influence pathogenicity, immune response, and vaccine efficacy, making it an important subject of research. Global research results in this area highlight the importance of causative agent of chickenpox genetic monitoring for understanding its evolution and developing effective vaccination and treatment strategies. These results may be useful for epidemiologists, immunologists, virologists, and infectious disease specialists.

Our target point within this following steps, is prostate cancer. Prostate cancer is classified structurally, by its Gleason Score. Phosphatases are implicated in different cell alterations, including proliferation, differentiation and carcinogenesis. In specific life circumstances, proteins are regulators with implications in intracellular signaling pathways. Alterations in phosphatases functionality represent a key point in malignancy development. Researchers try to investigate and to conclude on prostate cancer using also genomic analyses, clinically useful biomarkers and imagistic methods. So finally after following description steps, purposed aim is to conclude on prostate cancer and different key points abordation.

Objective. To assess the levels of navigational and vaccination literacy among students of three universities in Karaganda city and to identify factors influencing these indicators.

Materials and Methods. The cross-sectional study involved 1,327 students from Buketov Karaganda University, Abylkas Saginov Karaganda Technical University, and Karaganda Medical University. International questionnaires HLS19-NAV and HLS19-VAC, translated into Russian and Kazakh and validated in Kazakhstan, were used. Collected data on socio-demographic characteristics, health-related behaviors, and self-assessed health were analyzed using descriptive statistics, Pearson’s correlation analysis, t-tests, ANOVA, and linear regression.

Results. The average navigational literacy score among all respondents was 87.18±14.16 (excellent level), and the average vaccination literacy score was 82.6±20.2 (good level). The highest navigational and vaccination literacy scores were identified among students of medical specialties. Respondents previously trained in basic life support skills had significantly higher levels of navigational and vaccination literacy (p<0.001). Financial accessibility of medications and medical services also positively correlated with literacy indicators (p<0.05). However, students who consumed alcohol or had chronic diseases exhibited lower navigational literacy and/or vaccination literacy scores.

Conclusions. The average levels of navigational and vaccination literacy were higher among students of medical specialties, and both the year of study and the presence of basic life support skills positively correlated with literacy levels. According to multiple linear regression results, factors statistically significantly influencing the increase of navigational and vaccination literacy included: urban residential area, possession of basic medical assistance skills, and higher socio-economic status. Factors leading to the decrease in navigational and vaccination literacy included: family health problems, difficulty in accessing medical services, and chronic diseases.

Aim. The development of a liquid chromatography method for the quantitative determination of Sulfamethoxazole and Carbamazepine in wastewater from sewage systems and surface waters of the city of Shymkent.

Materials and methods. The chromatographic system DIONEX UltiMate 3000 with diode-array detector at absorption wavelength of 254 nm, reversed-phase version with mobile phase of acetonitrile-water composition (40: 60) and with a Hypersil GOLD C8 150x2.1 mm 1.9 micron column filled with porous ultrapurified silica gel, the thermostat temperature of the chromatographic column was 30 0C. Elution was carried out in isocratic mode. The total analysis time for 1 sample was 30 min. The flow rate of mobile phase was 1 ml/min. The retention time of standard sample solutions of carbamazepine was 3.612±0.1 min, for sulfamethoxazole – 6.910±0.1 min.

Results and discussion. A validated method for the detection and quantification of drug residues in water samples using the UHPLC-DAD method has been developed: the correlation coefficient of the linear regression graph was 0.9999; the relative standard deviation of the method for sulfamethoxazole and carbamazepine between samples within a cycle was 0.08110.7354%, between cycles – 0.1660-1.6457%. Monitoring of drug contamination of the studied waste and surface waters were carried out. At low concentrations, sulfamethoxazole and carbamazepine were detected and quantified in waste and surface waters of the Shymkent city. Under chromatographic conditions, the retention time of carbamazepine was 3.612±0.1 min, of sulfamethoxazole – 6.910±0.1 min, which corresponds to the retention times of the standard sample solutions.

Conclusions. A method for the study of water samples for the content of pharmaceutical residues using HPLC-DAD was developed and validated: the correlation coefficient of the linear regression graph was 0.9999; the relative error for carbamazepine ranged from 0.0166% to 1.6457%, and for sulfamethoxazole from 0.3888% to 0.8212%, confirming the high reproducibility of the developed method, which is suitable for further analytical research.

Based on the results of the study of water samples, the quantitative content of carbamazepine and sulfamethoxazole in wastewater and surface waters of Shymkent was determined during the initial study in the autumn period. The results of preliminary studies form the basis for further research on wastewater and surface waters for the presence of pharmaceutical residues to monitor the ecological situation in the region.

Aim. Analysis of the incidence rate among patients undergoing treatment at the «Densaulyk» Medical Rehabilitation Center in Shymkent city.

Materials and methods. Analysis of the medical and social characteristics of patients of Medical Rehabilitation Center based on patient case histories for 2022-2023. The total population amounted to 3,000 people per year, the sample size was 380 people. Data were calculated in separate age groups for men and women. The calculations were performed on a personal computer using the Excel-2007 application program.

Results and discussion. The average age of patients among men and women was 67.3 years (men – 66.53 years, women – 68.03 years). The majority of patients are persons of retirement age (302 (79.4%). The priority are diseases of the circulatory system (179 (47.11%) and diseases of the musculoskeletal system (123 (32.37%). The greatest comorbidity is typical for patients of middle, elderly and senile age. Among the concomitant diseases, diseases of the circulatory system, musculoskeletal, respiratory, digestive, endocrine and nervous systems occupy priority positions.

Conclusions. The structure of patients by gender difference, the class of the underlying disease, depending on the age group, has significant differences. The increasing level of comorbidity with increasing age of patients creates prerequisites for the creation of conditions and the development of treatment technologies that could have a complex effect on various diseases.

Aim. To assess the level of awareness of pupils (grades 9-10) of secondary schools in Karaganda city regarding rational nutrition.

Materials and methods. As a part of a cross-sectional study, the level of awareness of pupils (grades 9-10) of secondary schools in Karaganda city regarding rational nutrition was assessed using the active questionnaire survey. 400 students aged 14-15 took part in the survey. Before the questionnaire survey, the respondents were informed about the research objectives, and the confidentiality and anonymity of the answers were guaranteed. Statistical data processing was performed using Microsoft Office Excel 2007 software.

Results and discussion. The analysis of the survey results demonstrated the insufficient level of knowledge among students regarding rational nutrition. Only 43% pupils were able to correctly answer the question of which substances are the main source of energy in the body. 56% pupils demonstrated knowledge about the plastic role of proteins in the human body. Only 14% pupils new the «alimentary-dependent diseases» concept. The majority of respondents associated rational nutrition only with the prevention of obesity, diabetes and anorexia.

So, 23.3% respondents believed that less than 400 grams of vegetables and fruits are enough in the daily diet, 17.8% believed that only vegetables should be in the daily diet, since fruits contribute to weight gain and have a harmful effect on health. 88% pupils were convinced that gluten «glues blood vessels and intestines», promotes weight gain and the development of inflammatory processes. 68.5% respondents believed that washing down food with liquid is harmful, as liquid can «dilute» gastric juice and disrupt the digestion of food. 59.5% pupils adhere to the myth of the dangers of eating after 18:00.

Conclusions. The results of the study demonstrate a low level of awareness among schoolchildren regarding rational nutrition, which can lead to the formation of irrational eating behavior in them and, as a result, a prerequisite for the development of alimentary-dependent diseases. It is necessary to develop and implement educational programs aimed at improving the level of literacy of adolescents in matters of healthy nutrition. This will reduce the risks associated with the occurrence of functional disorders and diseases in the future.

Relevance. The physiologic course of pregnancy depends on the proper formation of the placenta, the key element of which is the vascular system. Its development is determined by trophoblast invasion, vasculogenesis and angiogenesis. Placental growth factor (PlGF) is an angiogenic protein that promotes vascular development. Its high level in the placenta is associated with active formation of the vascular network, peaks by week 30, and then gradually decreases thereafter. Despite numerous studies of biologically active substances in early pregnancy, data on the dynamics of angiogenic and antiangiogenic factors throughout gestation are insufficient and contradictory.

Aim. To study the level and relationship of placental growth factor in the blood and urine during pregnancy.

Materials and methods. A cross-sectional study was conducted, which included 304 pregnant women. A general clinical examination was analyzed, the level of systolic and diastolic blood pressure was determined. Blood and urine samples were also taken to determine the level of placental growth factor.

Results and discussion. The average age of the subjects was 27.44±4.99 years. The mean concentration of placental growth factor in the blood of all participants was 35.5 (22.4±51.2) pg/ml, and in urine was 20.8 (13.8±34.6) pg/ml. When assessing the correlation between PlGF concentrations in blood and urine in the first trimester of pregnancy, an average positive correlation of r=0.62 (95% CI: 0.54; 0.68, p<0.0001) was revealed. Next, we analyzed the dependence of the dynamics of SBP, DBP and proteinuria depending on the concentration of PlGF in the blood and urine of pregnant women: low concentration of PlGF in the blood and urine was significantly associated with an increase in systolic and diastolic blood pressure in the 3rd trimester of pregnancy (p<0.0001).

Conclusions. The average concentration of placental growth factor in the blood and urine in the first trimester is 35.5 pg/ml and 20.8 pg/ml, respectively. The level of PlGF in the blood has a moderate positive correlation with the concentration of PlGF in the urine. Low concentrations of PlGF in the blood and urine were statistically significantly associated with the increase in systolic and diastolic blood pressure in the 3rd trimester of pregnancy (p<0.0001).

Aim of the study. The aim of the study was to evaluate the status parameters of elderly and senile people in Central Kazakhstan with certain alimentary-dependent diseases (obesity, diseases of the circulatory system, diseases of the endocrine system).

Materials and methods. During the cross-sectional study of 300 people aged 60 to 90 years: elderly (60-74 years) and senile (75-90 years), nutritional status assessment data were analyzed: physical examination and anthropometry – body mass index, skin thickness fat folds; biochemical parameters (glucose, cholesterol, creatinine, urea and triglycerides in the blood).

Results and discussion. In group I (61-74 years old) the median weight was 79 kg, and in group II (75 years and above) – 74 kg. The median body mass index in group I was 30.04, in group II – 28.6. The median glucose level in group I was 6.5 mmol/l, in group II – 6.1 mmol/l. The median cholesterol in group I was 5.5 mmol/l, in group II – 5.4 mmol/l. The median urea in group I was 5.6, in group II – 6.5. Body mass index was high and indicate overweight and obesity. Glucose and cholesterol levels in both groups were increased, indicating the effect of foods with the high glycemic index. The urea level in group II was higher than in group I, which may indicate the greater consumption of salty foods.

Conclusions. The average body mass index in both groups of elderly and senile people didn`t correspond to the norm, was significantly higher and indicate the presence of excess body weight. The average data for glucose and cholesterol levels in both groups have large increases, indicating an indirect effect of excessive consumption of high-fat foods with a high glycemic index. The level of urea in group II (75 years and above) individuals is significantly higher than in group I (61-74 years), which indicates a greater consumption of foods with salt. The study results confirm imbalance and malnutrition, exacerbating existing nutrition-dependent diseases.

Objective. Double negative T cells are involved in various neoplastic processes including hematologic malignancies such as acute lymphoblastic leukemia. These unconventional lymphocytes express neither CD4 nor CD8 and play a role in immune modulation in cancer, particularly in the bone marrow microenvironment. However, their specific involvement in acute lymphoblastic leukemia and other leukemias, especially in pediatric patients, remains poorly understood. The present pilot study aims to characterize double negative T-cells in children with acute lymphoblastic leukemia and compare them with healthy controls.

Materials and methods. A prospective, cross-sectional study of 20 children diagnosed with acute lymphoblastic leukemia and 9 healthy, ageand sex-matched control participants was performed. Flow cytometry was used to evaluate lymphocyte subpopulations, including double negative T-cells.

Results and Discussion. The total number of double negative T cells significantly increased in patients with acute lymphoblastic leukemia compared to controls. In particular, αβ+DNT cells were markedly increased in patients with acute lymphoblastic leukemia both in percentage and absolute values. At the same time, γδ+DNT cells were significantly decreased in patients with acute lymphoblastic leukemia in absolute number and in proportion to CD3+ lymphocytes.

Conclusions. αβ+DNT cells are significantly elevated in children with acute lymphoblastic leukemia, suggesting their possible role in the immune response to leukemia. However, this increase may reflect a broader immune dysregulation rather than being specific to acute lymphoblastic leukemia. Further studies are required to clarify their role in leukemia and to explore their therapeutic potential.

Background. Arterial hypertension remains one of the leading causes of cardiovascular complications and mortality worldwide. A key factor in effective AH management is high adherence to medication therapy; however, adherence levels remain insufficient. In recent years, digital technologies, including mobile applications designed to enhance treatment adherence, have been actively developing, yet data on their effectiveness remain limited.

Aim. To evaluate the impact of the mobile application CardioExpert.kz on treatment adherence and blood pressure control in patients with primary hypertension within a randomized controlled trial.

Materials and methods. The study included 633 patients with primary hypertension who were randomized into two groups: a control group (standard treatment) and an experimental group (using the mobile application). The primary efficacy indicators were changes in systolic and diastolic blood pressure levels, as well as treatment adherence assessed using the MMAS-8 scale. Results and discussion. After 1 month of observation, the experimental group showed a significant reduction in systolic (-10.74±20.89 mmHg) and diastolic blood pressure (-2.52±12.84 mmHg) compared to the control group (р<0.001).

Additionally, a statistically significant improvement in medication adherence was recorded (р<0.001).

Conclusions. The use of a mobile application demonstrated a positive effect on blood pressure control and adherence to treatment in patients with hypertension. However, further studies with a longer follow-up period are needed to assess the long-term effectiveness of digital technologies in hypertension management.

Aim. To carry out a histological and histomorphometric assessment of bone tissue regeneration processes using a bone allograph prepared according to the Marburg bone bank system in combination with rhBMP-2 on a rabbit femoral defect model.

Materials and methods. In this study, 2 groups were formed, each with 24 subjects (rabbits), who had a defect with a diameter of 5 mm in the distal metaphysis of the femur. In group 1, the defect was filled with bone allograft in combination with rhBMP-2. In group 2, the defect was filled with bone allograft without additional drugs. Further, histological and statistical processing of the obtained data was carried out.

Results. On day 14, in the AG+rhBMP-2 group, newly formed bone tissue amounted to 34.75±5.67% of the total area of the cortical plate defect. On day 30, in the AG+rhBMP-2 group, the closure of the cortical plate defect was 79.12±14.32%, the newly formed bone tissue covered 80.75% of the length and 71.37% of the thickness of the cortical plate. On day 60 in the AG+rhBMP-2 group, newly formed bone tissue covered the total area of the cortical plate defect by 64.50±27.73%, length by 62%, and thickness by 65.25%.

Discussion. The data obtained indicate an acceleration of osteoregeneration in the early stages of bone plate restoration in the AG+rhBMP-2 group, however, the results obtained by 60 days were extremely heterogeneous, indicating the dysenergic effect of rhBMP-2 on mesenchymal progenitor cells and the associated excessive resorptive effect of rhBMP-2 in some cases.

Conclusion. According to the results of this study, it can be seen that the use of bone allograft in combination with rhBMP-2 at the late stages of bone regeneration leads to unsatisfactory results, which manifests itself in the form of high heterogeneity of the data obtained, among which, in a significant part of cases, there is not sufficient closure of the defect with newly formed bone tissue.

In the modern pharmaceutical industry, the application of artificial intelligence significantly enhances the process of drug development. Recent studies have revealed that artificial intelligence can notably improve the effectiveness of hypertension treatment by optimizing the compositions of herbal blends.

This study proposes three unique formulations of blends developed using the ChatGPT neural network. The three devised blend compositions are formulated based on the analysis of plant data, their interactions, and treatment effectiveness. Each composition is meticulously selected to ensure maximum efficacy and minimal side effects. These innovative approaches have the potential to significantly enhance patients' quality of life by providing them with more effective and safer means for treating hypertension and other cardiovascular conditions. This progress opens up new perspectives for future medical development, emphasizing the significance of the symbiosis between technology and medical practice.

Aim. Investigation of the chemical composition of drilling fluid and its toxicity based on the assessment of average lethal doses.

Materials and methods. The chemical composition of drilling fluid and drilling mud for metals and inorganic oxides was studied by atomic absorption spectroscopy (AgilentAA240FS), as well as using atomic emission spectroscopy. In an experiment on mature male rats, the average lethal dose of drilling fluid was established with intraperitoneal single injection.

Results and discussion. The results of our own research presented in this paper indicate that drilling fluid and drilling mud have a diverse chemical composition due to the presence of heavy metals and inorganic oxides in them. Pb and As are found in the drilling fluid, and As, Ba, Cd, Cr, Cu, Mn, Ni, Pb, Zn; P₂O₅, SiO₂, CaO, Na₂O, and K₂O in the drilling mud. In acute experience, under conditions of a single intraperitoneal injection of drilling fluid, lethal doses (LD₁₆, LD₅₀, LD₈₄, LD₁₀₀), as well as survival rates, were established. The dose-dependent effects of the toxic effect of drilling fluid, determined by the average lethal dose and the corresponding survival rate, indicate the potential danger of drilling fluid and drilling mud.

Conclusions. Drilling fluid and drilling mud have a certain toxicity and danger, which largely depends on their chemical composition due to the presence of heavy metals and inorganic oxides. The established lethal doses and survival rates indicate moderate toxicity of drilling fluid.

In the context of constant changes in medical technologies, the dynamic development of scientific research and changing needs of patients, it is necessary to constantly improve the work of medical institutions. This is especially true for perinatal centers, where every detail plays a crucial role in taking care of the health of expectant and new mothers and their babies. Improving the quality of services provided in the Regional Perinatal Center of Taldykorgan city is not only an urgent, but also a vital task aimed at improving the health of the region's population. In the course of the study, we analyzed the works of such authors as: et al. they may be of interest for further study of the issue.

Aim. To analyze innovative approaches aimed at improving the quality of medical care in the Regional perinatal Center of Taldykorgan city.

Materials and methods. To achieve this goal, a set of studies was carried out, including expert assessments, patient questionnaires and observations of the doctors' work process.

Results and discussion. The results of the study may be valuable for the development of specific strategies and recommendations to improve the quality of medical care in the Regional Perinatal Center of Taldykorgan city.

Conclusions. The obtained data will allow for a deeper analysis of the current situation and identify key problematic aspects in the provision of medical services.

Heart failure with preserved ejection fraction represents a significant clinical and social challenge requiring a personalized approach to diagnosis and treatment. Physicians' awareness of the diagnosis and management of patients with heart failure with preserved ejection fraction is a key factor determining the quality of medical care. The characteristics of heart failure with preserved ejection fraction require physicians to have specialized diagnostic skills, such as assessment of diastolic function and structural changes of the heart, including the use of natriuretic peptides and echocardiography. This study aimed to develop and validate a questionnaire assessing physicians’ awareness of issues related with heart failure with preserved ejection fraction. The study involved a systematic literature review, expert evaluation, and pilot testing of the questionnaire with 151 physicians.

The developed questionnaire comprises 18 questions covering professional practice, diagnostic criteria, use of biomarkers, prevention and education, as well as patient challenges and adherence. The reliability and validity of the questionnaire were confirmed through statistical methods.

The study highlights the importance of specialized educational programs to enhance knowledge and improve medical care for patients with heart failure with preserved ejection fraction. The findings offer valuable insights for optimizing the diagnosis and management of heart failure with preserved ejection fraction, reducing hospitalization rates, and improving patient quality of life.

In this regard, special attention should be paid to the development of professional competencies of all specialists in the field of healthcare and pharmacy. The development of key competencies of future pharmacists is an important factor in their competitiveness in the global pharmaceutical space. The results of introducing into the educational process the technology for assessing the practical skills of students of the 5th year of the educational program "6B10103-Bachelor's Pharmacy" in the discipline "Quality control and standardization of medicines" at the stage of intermediate certification are given in the article. The authors come to the conclusion that, along with the use of active teaching methods in the educational process, the need to improve and introduce various forms of intermediate assessment of knowledge in specialized disciplines arises. Such pedagogical technologies make it possible to carry out a more objective assessment of the acquired skills in the examination of medicines in conditions close to the real pharmaceutical practice of conducting control and analytical measures.

The article is devoted to the problem of teaching Russian as a foreign language in Kazakh language groups at noncore universities. The author focuses on the topical issues of using innovative technologies in teaching reading. The formation of reading skills, especially those studying reading, is very relevant today, as new information technologies are developing, new sources of information are appearing – more compact, flexible and mobile, there is no reading culture, the interests and needs of students are changing. The aim of the article is to identify the possibilities of such a tools as word cloud, mind map, infographic and time line in sequential teaching of different types of reading in the process of teaching Russian as a foreign language in a non-philological audience and to demonstrate its effectiveness by specific examples. The article is devoted to concrete examples of new technologies application in the practical Russian as a foreign language classes at the university. In the article, the special attention is paid to the formation of skills of the main type of reading – learning reading.

In particular, lessons on several topics contained in the standard program on Russian as a foreign language at a university are considered in detail as a sample. These classes have been tested in teaching first-year students of NC JSC «Karaganda Medical University».

As a result of the analysis, the author comes to the conclusion that new technologies in combination with traditional work on text are effective tool for teaching reading of non-core university students. New technologies create an engaging and motivating learning environment, so they encourage students to actively participate in the learning process and motivate them to read.

Aim. Explaining the importance of the subject of cultural studies for medical students, to prove that this subject is a key decisive factor in social development.

Materials and methods. The published works on this topic were studied and used as the scientific and methodological basis of the article. When considering and analyzing the works of scientists dealing with the problem of grouping studies, they were carried out on the basis of the historical-objective principle using methods: historical-objective, logical, systematic, comparative analysis, etc.

Results and discussion. The relevance of education in teaching cultural studies in medical education is analyzed. The integrative nature of cultural studies expands the formation of cultural competencies in any field. In addition to purely educational tasks, cultural studies show a close ontological connection between medicine and culture. Medicine cannot be limited in its knowledge of man only to rational, logical aspects. A doctor is obliged to see and feel the emotional and spiritual side of a person, take into account its significance in the process of performing professional duties, and be able to influence them.

Conclusions. Defining the interdisciplinary nature of cultural studies and the content of the subject of research, the authors pay attention to the interpretation of the term “culture” in the educational space of medical universities and consider the relationship between culture and medicine. Having identified the possibility of a union of culture and medicine, the authors were given the concept of “medical culture.” Medical culture is a complex and multifaceted sociocultural phenomenon, which reflects the health and quality of life of the individual and society as a whole, and the characteristics of human life. Considering the integrative nature of cultural studies, the authors point to its unique capabilities in the field of developing general cultural and professional competencies. As a result of the analysis, the position on the need for cultural knowledge in medical education is proven.