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A CASE OF ORTHOTOPIC BICAVAL HEART TRANSPLANTATION IN A PATIENT WITH PERIPARTUM CARDIOMYOPATHY

https://doi.org/10.59598/ME-2305-6053-2025-116-3-166-169

Abstract

This paper presents a clinical case of orthotopic bicaval heart transplantation in a patient with end-stage chronic heart failure that developed against the background of peripartum cardiomyopathy. The disease manifested itself in the second trimester of pregnancy, complicated by severe preeclampsia and progressive heart failure. In the absence of an available donor organ, the patient was implanted with a left ventricular assist device HeartMate 3 as a «bridge to transplantation». Four years after left ventricular assist device implantation, when a donor appeared, orthotopic heart transplantation was successfully performed. The case demonstrates the effectiveness of a multidisciplinary approach in conditions of a limited donor resource and emphasizes the need for early diagnosis, systemic prevention and development of transplantation services to improve outcomes in patients with peripartum cardiomyopathy.

About the Authors

M. Bekbosynova
University Medical Center Corporate Fund
Kazakhstan

010000, Astana с., Turan ave., 38



S. Jetybayeva
University Medical Center Corporate Fund
Kazakhstan

010000, Astana с., Turan ave., 38



A. Sailybaeva
University Medical Center Corporate Fund
Kazakhstan

010000, Astana с., Turan ave., 38



A. Taukelova
University Medical Center Corporate Fund
Kazakhstan

010000, Astana с., Turan ave., 38



Zh. Aldanysh
University Medical Center Corporate Fund
Kazakhstan

Zhumazhan Aldanysh 

010000, Astana с., Turan ave., 38



А. Kushugulova
University Medical Center Corporate Fund
Kazakhstan

010000, Astana с., Turan ave., 38



References

1. McDonagh T.A., Metra M., Adamo M. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur. Heart J. 2021; 42 (36): 35993726.

2. Patten I.S., Rana S., Shahul S. Cardiac angiogenic imbalance leads to peripartum cardiomyopathy. J. Vasc. Res. 2019; 56 (1): 11-15.

3. Kamiya C.A., Kitakaze M., Ishibashi-Ueda H. Different characteristics of peripartum cardiomyopathy between patients complicated with and without hypertensive disorders. Results from the Japanese Nationwide survey of peripartum cardiomyopathy. Circ. J. 2011; 75 (8): 19751981.

4. Ministry of Health of the Republic of Kazakhstan. Clinical protocol for heart transplantation. [Cited 2025 May 15]. Available from: https://diseases.medelement.com/disease/трансплантация-сердца-2017/15630

5. Lee S., Cho G.J., Park G.U. Incidence, Risk Factors, and Clinical Characteristics of Peripartum Cardiomyopathy in South Korea. Circ. Heart Fail. 2018: 11: 4.


Review

For citations:


Bekbosynova M., Jetybayeva S., Sailybaeva A., Taukelova A., Aldanysh Zh., Kushugulova А. A CASE OF ORTHOTOPIC BICAVAL HEART TRANSPLANTATION IN A PATIENT WITH PERIPARTUM CARDIOMYOPATHY. Medicine and ecology. 2025;(3):166-169. https://doi.org/10.59598/ME-2305-6053-2025-116-3-166-169

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ISSN 2305-6045 (Print)
ISSN 2305-6053 (Online)