The article analyzes the literature on the diagnosis of lung changes in coronavirus infection (CVI) COVID-19 by methods of radiation diagnostics. The incidence of coronavirus around the world in the period from 2019 to 2021 was registered over 250 million people, there is an upward trend. In Kazakhstan, the identified cases of 980860 and more than 12887 deaths as a result of coronavirus [9]. The World Health Organization assigned the status of a pandemic to the COVID-19 coronavirus infection on March 11, 2020 [46]. To verify the diagnosis of COVID-19 coronavirus infection, laboratory methods for detecting SARS-CoV-2 RNA are mainly used. The widespread use of methods of radiation diagnostics plain radiography and computed tomography is facilitated by its leading manifestation - damage to the lung tissue. International statistical indicators reflect the impact of the COVID-19 coronavirus infection, namely, its scale, a pandemic, on the structure of diagnostic studies, namely the predominance of radiation diagnostics methods. The use of this or that method lies in the experience of different regions, which differ greatly depending on social norms and the instructions of the health authorities. CT is a priority in countries by the widespread use of isolation / hospitalization of all infected patients in circumstances where the reliability and availability of testing for COVID- 19 is limited and the lead time is long (for example, Russia, China). According to 50 radiology departments from 33 countries, visualization of changes in the lungs with suspected COVID-19 infection is 89%, with confirmed COVID-19 it is 94%, with severe symptoms 100%, with critical conditions 100% [46]. In addition, this type of study allows you to detect signs of viral damage to the lung tissue both with positive and negative PCR results, in asymptomatic patients, to carry out differential diagnostics with other diseases, to assess the severity of the lesion and prognostic ally unfavorable signs of development, the effectiveness of therapy, and the presence of complications.

The article presents the results of a sociological study that was conducted at the Center for special social services №3 in Karaganda in October 2021. Based on the results of the study, an analysis was made of the emotional state of the nurses of the institution and its impact on health. On the basis of the study, proposals were developed for a medical institution aimed at improving the quality of life of nurses.

The review presents the results of an analysis of data from domestic and foreign literature about preeclampsia, which is one of the main causes of perinatal morbidity and mortality. Women with preeclampsia subsequently have an increased risk of developing cardiovascular complications. The main clinical and pathogenetic mechanisms affecting the occurrence of preeclampsia are considered.
The main attention in the work is focused on the characteristic features of the clinical course, bio-chemical predictors of preeclampsia sflt-1/PIGF, PAPP-A, features of the echocardiographic manifestation of prеeclampsia and its association with cardiovascular diseases in the distant period.

The present study refers to the exploration of the respiratory function of patients who presented acute symptoms of chronic obstructive pulmonary disease. In the medical specialty units, examination was performed using a standard chest X-ray imaging investigation; followed by a spirometry test, according to the patient's severity of symptoms, using the betamimetics test. Both the X-ray result and the imaging investigation of spirometry showed changes. Changes varied according to the patients from different investigate disease groups in relation to chronic obstructive pulmonary disease.

Appendix pathology brings together different forms and is found in different age segments. Most susceptible to disease are children. In this context, the children and young people Appendix pathology may be complicated or can be accompanied by damage to adjacent organs, located in the abdominal cavity.
This morphological study presents the structural aspects of normal appendix and the ulcerated appendicitis. For observation of structural aspects, has been used classic stainings. It also shows the appendix using immunohistochemical technique.

This work discusses a comparative analysis of the characteristics of the course of pregnancy and the outcome of childbirth in pregnant women with nicotine addiction, as well as the effect on intrauterine development and perinatal outcomes. To carry out the work and obtain complete information on the obstetric and gynecological history, 90 histories of births of women and their newborns were analyzed. Analyses of our work show that smoking during pregnancy leads to such complications of pregnancy as the development of chronic placental insufficiency, various types of IUGR of the fetus and low birth weight babies to the gestation period.

Lyell's syndrome is a severe polyetiological disease of allergic nature, characterized by sharp violation General state of the patient, bullous lesions throughout the skin and mucous membranes.
It received its main name in honor of the doctor Lyell, who first described in 1956 as a severe form of toxicoderma. This syndrome in subsequent years tends to increase among all age groups (including infants), due to the widespread use of chemotherapy among all age groups.
The most common causes of Lyell's syndrome are sulfonamides, antibiotics (especially penicillin, streptomycin and tetracyclines), salicylic acid derivatives, pyrazolone, barbiturates, dysentery bacteriophage, anti-tetanus serum. It is especially dangerous to use “therapeutic cocktails”, consisting of a mixture of different drugs, usually antibiotics, sulfonamides, anti-inflammatory, anti-pyrexic drugs.
Lyell's syndrome is a rare disease. At any age, most often in people aged 20-40 years , earlier children occur during the first three years of life. Lyell's syndrome is a total frequency of 0.4 to 1.2 cases per 1 million population, found in 0.3% of cases of drug Allergy. According to various data, mortality in Lyell's syndrome ranges from 30% to 70%, since Lyell's syndrome from severe course in 30-50% of patients there is a risk of death within 5-30 days from the date of the disease. Seasonal increase of the disease is recorded in the winter day and early spring. In the treatment of the disease and possible re-disease. In the literature there are few publications on this topic and on modern methods of treatment.
The prognosis of the disease is determined by the nature of its course. In this regard, there are 3 variants of the course of Lyell's syndrome: acute lethal outcome, lethal outcome at the confluence of an acute infectious process and, as a rule, favorable after 7-10 days of treatment. Early start of therapeutic measures and their careful implementation improve the prognosis of the disease. This syndrome is one of the most important topics in medicine, it is considered as an autoimmune, autoallergic disease in pathogenesis.