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INFLUENCE OF REGEL'S EMINIUM EXTRACT ON LIPID PEROXIDATION AND ANTIOXIDANT PROTECTION IN PERIPHERAL ORGANS OF IMMUNOGENESIS DURING COMBINE ACTIONS OF FRACTIONAL DOSE OF GAMMA RADIATION AND EMOTIONAL STRESS

Abstract

In the experiment, the effect of Regel's Eminium extract on lipid peroxidation and antioxidant system in peripheral organs of immunogenesis was studied under the combined action of a fractionated dose of gamma radiation and emotional stress. The results show that in the lymphatic nodes of the small intestine with the action of Regel's Eminium extract, combined with emotional stress and irradiation of the fractionated dose of gamma radiation in the early and late stages of the general adaptation syndrome, the level of lipid peroxidation and glutathione reductase contents increase; in the late stage of general adaptive syndrome, the levels of conjugated dienes and malondialdehydes were significantly lower than the control values. Under the action of Regel's Eminium extract in peripheral blood lymphocytes in combination with emotional stress in the irradiated fractionated dose of gamma radiation, the level of primary and secondary products of lipid peroxidation increases in the early stage of the general adaptation syndrome, the conjugated dienes and malondialde-hydes levels are significantly lower than the control values. There was an increase in the content of glutathione reductase and glutathione peroxidase, which indicates the activation of the antioxidant system

About the Authors

B. A. Zhetpisbayev
State medical university of Semey
Kazakhstan


G. T. Nurmadiyeva
State medical university of Semey
Kazakhstan


Zh. U. Kozykenova
State medical university of Semey
Kazakhstan


A. S. Argymbekova
State medical university of Semey
Kazakhstan


L. A. Ibragimova
State medical university of Semey
Kazakhstan


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Review

For citations:


Zhetpisbayev B.A., Nurmadiyeva G.T., Kozykenova Zh.U., Argymbekova A.S., Ibragimova L.A. INFLUENCE OF REGEL'S EMINIUM EXTRACT ON LIPID PEROXIDATION AND ANTIOXIDANT PROTECTION IN PERIPHERAL ORGANS OF IMMUNOGENESIS DURING COMBINE ACTIONS OF FRACTIONAL DOSE OF GAMMA RADIATION AND EMOTIONAL STRESS. Medicine and ecology. 2018;(4):95-104. (In Russ.)

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