EVALUATION OF EXPECTORANT ACTIVITY OF THE TOTAL EXTRACTS OF THYMUS SERPYLLUM L.S.L., GROWING ON THE TERRITORY OF KAZAKHSTAN

Im: to study the expectorant activity of dry total extracts of two chemotypes of thyme creeping ( Thymus serpyllum Ls.l.) collected in the territory of Kazakhstan. Materials and methods: to evaluate the expectorant effect of dry total extracts of two chemotypes of thyme creeping collected in the populations of the Karaganda region in the Korneevsky forests and forests of Karkaralinsk, was used studying the motor function of the ciliary epithelium of model of the frog's esophagus by the method Gatsura. Experimental work was performed on the autumn frogs Rana Temporarea. Results and discussioi: it has been experimentally established that the dry total extract of creeping thyme growing in the forests of Karkaralinsk has expectorant activity comparable to the reference preparation - Bronchicum C syrup, and the dry total extract of creeping thyme collected in the Korneevsky forests has a less pronounced expectorant effect. Conclusion: dry total extract of creeping thyme, which grows in the forests of Karkaralinsk, is a promising substance for the development of a domestic medicine for expectorant action.

Thymus serpyllum L.s.l, dry total extract, expectorant activity

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