Kidney damage in endocrine diseases in children

The relevance of the problem of kidney damage in children with obesity, diabetes mellitus , metabolic syndrome is due to the increased frequency of nephropathy associated with metabolic disorders, the tendency to their progressive course and the need to optimize early diagnosis. The purpose of the study was to determine the clinic of kidney damage in children with endocrine pathologies.
In the complex medical information system DamuMed, an analysis of primary medical documentation and a clinicalparaclinical examination of children suffering from endocrine pathologies were carried out: type 1 diabetes, obesity, the period 2018-2021 from 3 to 17 years. Patients were divided into the following groups: children without signs of kidney damage (62 children) and children with signs of kidney damage (75 children).When studying urinary system infections in children with Type 1 diabetes mellitus, bacteriuria in the main group was 32±2.47%, compared to the control group – 19±4.45%, p≤0.01 more often.
We tested 75 children aged 3 to 18 years with Type 1 diabetes for microalbuminuria. Microalbuminuria was detected in 34 children, which was 51.6%. In 93% (n = 27) of obese children, complications were detected: arterial hypertension (80%, N = 24) and dyslipidemia (27%, N = 8), which are predictors of kidney damage. The risk of developing and exacerbating kidney damage in children increases with the degree of obesity (with an increase in body mass index).

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