The role of genetic polymorphisms in the development of gestational diabetes
Abstract
The literature review provides an assessment of gestational diabetes genetic mechanisms. Predisposition to gestational diabetes is identified as a combination of functionally unfavorable alleles of different gene groups, for which polymorphisms have been established. The analysis of gene polymorphism would serve for well-timed identification of women with an increased risk of gestational diabetes and the development of prevention and treatment measures.
About the Authors
D. T. Amirkhanova
Kagarandy Medical University
Kazakhstan
Kazakhstan
department of internal diseases
Karaganda
A. A. Serikbayeva
Kagarandy Medical University
Kazakhstan
Kazakhstan
department of internal diseases
Karaganda
F. U. Nildibayeva
Kagarandy Medical University
Kazakhstan
Kazakhstan
department of internal diseases
Karaganda
D. N. Sheryazdanova
Kagarandy Medical University
Kazakhstan
Kazakhstan
department of internal diseases
Karaganda
Z. B. Tauesheva
Kagarandy Medical University
Kazakhstan
Kazakhstan
department of internal diseases
Karaganda
M. N. Koval
Kagarandy Medical University
Kazakhstan
Kazakhstan
department of internal diseases
Karaganda
Z. M. Tutkushbayeva
Karaganda regional clinical hospital
Kazakhstan
Kazakhstan
Karaganda
References
1. Ajlamazyan E. K. Rol’ melatonina v razvitii gestacionnogo saharnogo diabeta / E. K. Ajlamazyan, I. I Evsyukova., M. I. YArmolinskaya // ZHurnal akusherstva i zhenskih boleznej. – 2018. – T. 67, № 1. – S. 85–91.
2. Ahmetova E. S. Patofiziologicheskie i geneticheskie izmeneniya v organizme beremennoj pri gestacionnom saharnom diabete // ZHurnal akusherstva i zhenskih boleznej. – 2017. – T. 66, №5. – C. 27-36.
3. Belyaeva I. A. Rol’ saharnogo diabeta tipa MODY v strukture gestacionnogo saharnogo diabeta / I. A. Belyaeva, A. K. Ovsyannikova, O. D. Rymar // Doktor.Ru. – 2021, № 11. – S. 68-72.
4. Gestacionnyj saharnyj diabet – geneticheskie aspekty / N. V. Bashmakova, T. B. Tret’yakova, O. B. Froluhina, E.G. Deryabina. // Problemy reprodukcii. – 2019. – T. 25, №6. – S. 22-28.
5. Dreval’ A. V. Gestacionnyj saharnyj diabet (po materialam skriningovogo issledovaniya v Moskovskoj oblasti) / A. V. Dreval’, T. P. SHestakova, I. V. Bunak // Al’manah klinicheskoj mediciny. – 2016. – V. 44, № 4. – S. 406-413.
6. Mutacii v genah yadernyh faktorov gepatocitov kak redkaya prichina diabeta u beremennyh / N. A. Zubkova, F. F. Burumkulova, V. A. Petruhin i dr. // Saharnyj diabet. – 2019. – T. 22, №3. – S. 274-280.
7. Nikonova L. V. Gestacionnyj saharnyj diabet: geneticheskie markery insulinorezistentnosti, diagnosticheskie kriterii i taktika vedeniya / L. V. Nikonova, S. V. Tishkovskij, O. S. Butrim // ZHurnal Grodnenskogo gosudarstvennogo medicinskogo universiteta. – 2020. – T.18, №6. – S. 732-738.
8. Pakin V. S. Molekulyarno-geneticheskie aspekty gestacionnogo saharnogo diabeta // Problemy Endokrinologii – 2017. – T 63, №3. – S. 204-207
9. Froluhina O. B. Kliniko-geneticheskie osnovy formirovaniya gestacionnogo saharnogo diabeta i narushenij uglevodnogo obmena posle zaversheniya beremennosti: avtoref. dis. …kand. med. nauk. – CHelyabinsk, 2021. – S. 24. Bai Y. The roles of ADIPOQ rs266729 and MTNR1B rs10830963 polymorphisms in patients with gestational diabetes mellitus: A meta-analysis/Yu Bai , Lei Tang , Ling Li , Ling Li and al. // Gene. – 2020. – 730:144302.
10. 10 Adiponectin gene polymorphisms and risk of gestational diabetes mellitus: A meta-analysis / L T. Huang, S L. Wu, X. Liao, et al. // World J. Clin Cases. – 2019. – V 7, №5. – P. 572-584.
11. Association of recently identified type 2 diabetes gene variants with Gestational Diabetes in Asian Indian population / S. Kanthimathi, M. Chidambaram, D. Bodhini et al. // Mol. Genet Genomics. – 2017. – V. 292, №3. – P. 585-59.
12. Ethnic differences in prevalence, risk factors, and perinatal outcomes of gestational diabetes mellitus: A comparison between immigrant ethnic Chinese women and Australian-born Caucasian women in Australia / C S. Wan, S. Abell, R. Aroni, et al. // J. Diabetes. – 2019. – V. 11, №10. – P. 809-817.
13. Fasting and post-prandial plasma glucose screening for gestational diabetes mellitus / H. Kansu-Celik, A. S. Ozgu-Erdinc, B. Kisa-Karakaya, et al. // East. Mediterr. Health J. – 2019. – V. 25, №4. – P. 282-289.
14. Fat mass and obesity-associated (FTO) gene epigenetic modifications in gestational diabetes: new insights and possible pathophysiological connections / M. Franzago, F. Fraticelli, M. Marchioni. et al. // Acta. Diabetol. – 2021. – V. 58, №8. – P. 997-1007.
15. Genetic susceptibility, lifestyle intervention and glycemic changes among women with prior gestational diabetes / Z. Liang, L. Wang, H. Liu, et al. // Clinical. Nutrition. – 2020. – V .39, №7. – P. 2144-2150
16. Genetic variants of TCF7L2 gene and its coherence with metabolic parameters in Lithuanian (Kaunas district) women population with previously diagnosed gestational diabetes mellitus compared to general population / M. Francaite-Daugeliene, V. Lesauskaite, A. Tamosiunas, et al. // Diabetes Research and Clinical Practic. – Available. – 2020.- http://www.elsevier.com/locate/diabres
17. Gestational diabetes mellitus / A. KautzkyWiller, J. Harreiter, D. Bancher-Todesca D., et al. // Wien Klin. Wochenschr. – 2016. – V. 128, №2. – P. 103-112.
18. Immanuel J. Screening and treatment for early-onset gestational diabetes mellitus: a systematic review and meta-analysis / J. Immanuel, D. Simmons // Curr. Diab. Rep. - 2017. – V .17, №11. – P. 115
19. Diabetes Atlas. – Brussels: IDF, 2019. – 8 th., ed. – P. 123.
20. Jawad F. Gestational diabetes mellitus in South Asia: Epidemiology / F. Jawad, K. Ejaz. // J. Pak. Med. Assoc. – 2016. – V. 66, №1. – P. 5-7.
21. Lack of association between IGF2BP2 rs4402960 polymorphism and gestational diabetes mellitus: a case-control study, meta-analysis and trial sequential analysis. / J. Liu, Song G, Zhao G, et al. // Biosci Rep.- 2020. – V. 40, №7 BSR20200990.
22. Lawrence R L. Prevalence of gestational diabetes according to commonly used data sources: an observational study. / R L. Lawrence, C R. Wall, F H. Bloomfield // BMC Pregnancy Childbirth. – 2019. – V. 19, №1. – P.349.
23. Molecular Biomarkers for Gestational Diabetes Mellitus / S.Dias, C. Pheiffer, Y. Abrahams, et. al. // Int J. Mol Sci. – 2018. – V. 19, №8. – P. 2926.
24. Molecular pathways disrupted by gestational diabetes mellitus / C. Nguyen-Ngo, N. Jayabalan, C. Salomon, M. Lappas // J. Mol. Endocrinol. – 2019. – V. 63, №3. – P. 51-72.
25. Novel Interleukin-10 Gene Polymorphism Is Linked to Gestational Diabetes in Taiwanese Population / J. Kang, C H. Liu, C N Lee, et.al. // Front Genet. – 2019 – V. 18, №10. – P. 89.
26. Peculiarities of the course of gestation and pregnancy outcomes in women with gestational diabetes mellitus / A. Meiramova , B Ainabekova , G Sadybekova, еt al. // Acta. Endocrinol. – 2018. – V. 14, №2. – P. 213-218.
27. Prevalence and risk factors of gestational diabetes mellitus in Asia: a systematic review and meta-analysis / KW. Lee, SM. Ching, V. Ramachandran, et al. // BMC Pregnancy Childbirth. – 2018. – V. 18, №1. – P. 494.
28. Prevalence of gestational diabetes among Chinese and South Asians: A Canadian populationbased analysis. / R O. Yeung, A. Savu, B. Kinniburgh, et al. // J. Diabetes Complications. – 2017. – V. 31, №3. – P. 529-536.
29. Prevalence of gestational diabetes mellitus in mainland China: A systematic review and meta-analysis. / C. Gao, X. Sun, L. Lu, et al // J Diabetes Investig. – 2019.- V, №1. – P. 154-162.
30. Polymorphism analysis of the Gly972Arg IRS-1 and Gly1057Asp IRS-2 genes in obese pregnant women / A. Górska, M. Wolek, B. Czerny et al. // Reproductive Biology. – 2020. – V. 20, №3. – P. 365-370.
31. TCF7L2 rs7903146 polymorphism modulates the association between adherence to a Mediterranean diet and the risk of gestational diabetes mellitus / A Barabash, J D Valerio, N Garcia, et. al. // Metabol. Open. – 2020. V. 26, № 8. – P. 100069.
32. The role of genetics and epigenetics in the pathogenesis of gestational diabetes mellitus/ J. Rosik, B. Szostak, F. Machaj, et al. // Ann. Hum Genet. 2020. – V. 84, №2. – P. 114-124.
33. The roles of ADIPOQ rs266729 and MTNR1B rs10830963 polymorphisms in patients with gestational diabetes mellitus: A meta-analysis / Yu Bai , Lei Tang , Ling Li, et al. // Gene. – 2020. – V. 730:144302.
34. Trends in the incidence of diabetes, its clinical sequelae, and associated costs in pregnancу / L. Jovanovič, Y. Liang, W Weng, et al. // Diabetes Metabolism Research and Reviews. – 2015. – V. 31, №7. – P. 707-716.
35. Yuen L. Ethnic Disparities in Gestational Diabetes / L. Yuen, V W. Wong, D. Simmons. // Curr Diab Rep.- 2018. – V. 18, №9. – P. 68.
Review
For citations:
Amirkhanova D.T., Serikbayeva A.A., Nildibayeva F.U., Sheryazdanova D.N., Tauesheva Z.B., Koval M.N., Tutkushbayeva Z.M. The role of genetic polymorphisms in the development of gestational diabetes. Medicine and ecology. 2022;(2):16-21. (In Russ.)
Views: 257
Email this article 