STUDY OF BIOMECHANICAL PROPERTIES OF A NEW BIOLOGICAL IMPLANT BASED ON EXTRACELLULAR BOVINE-DERIVED PERITONEUM MATRIX FOR ABDOMINAL WALL DEFECTS REPAIR

A prototype of a new biological implant - extracellular bovine-derived peritoneum matrix for abdominal wall reconstruction was developed and obtained. The aim was to study the biomechanical properties of the extracellular bovine-derived peritoneum matrix in comparison with the «Permacol» biological implant at the preoperative stage and after implantation (up to 180 days) in the experiment. The strength characteristics for elongation and rupture of the materials were studied experimentally. Based on the results of testing the samples, the extracellular bovine-derived peritoneum matrix demonstrates high mechanical strength, exceeding in 2 times than the comparison material "Permacol", mainly due to the elasticity. In the postoperative period, a multiple increase in the tensile strength is observed, both in the group with the extracellular bovine-derived peritoneum matrix, and in the comparison group where the acellular dermal collagen "Permacol" was used, while achieving an average values of absolute maximum of 14.5N and 15.9N respectively, without statistically significant differences, both at each observation period and totally in the experiment.

Permacol, extracellular bovine-derived peritoneum matrix, Permacol, abdominal wall defect, biomechanical properties, Permacol

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