Preview

Medicine and ecology

Advanced search

RISK ASSESSMENT OF THE DEVELOPMENT OF TYPE 2 DIABETES MELLITUS DEPENDING ON THE DEGREE OF ACTIVITY OF RHEUMATOID ARTHRITIS

Abstract

Objective: assess the risk of developing type 2 diabetes mellitus using the FINDRISC questionnaire in individuals with rheumatoid arthritis, depending on the degree of disease activity. Materials and methods: the study included 134 people, women 98 (73.1%) and 36 (26.9%) men aged 18 to 65 years with rheumatoid arthritis. The ten-year risk of diabetes was rated on the FINDRISC (Finnish Type 2 Diabetes Risk Assessment Form) scale. All respondents were divided into three groups depending on the level of activity of rheumatoid arthritis according to the Desease activity index 28-ESR scale (DAS28-ESR). Statistical processing of the material was carried out using IBM SPSS Statistiks v23 software, using the Kruskal-Wallace and Mann-Whitney indicators, the Spearman coefficient. Results and discussion: abdominal obesity (74.5%) and overweight (61.9%) prevailed in the structure of the frequency of risk factors for the development of type 2 diabetes. Significant differences between the comparison groups were found only by the criterion of eating vegetables (x2 = 7.899; p = 0.017). A correlation was found between the degree of activity of rheumatoid arthritis and the total score on the FINDRISC scale (p = 0.372; p = 0.00). Conclusion: the use of the FINDRISC questionnaire can be an effective tool for assessing the risk of type 2 diabetes in people with rheumatoid arthritis. Findings: a high degree of activity of rheumatoid arthritis increases the risk of developing type 2 diabetes in the next decade of life.

About the Authors

A. A. Shalygina
NC JSC Karaganda medical university
Kazakhstan


L. G. Turgunova
NC JSC Karaganda medical university
Kazakhstan


D. A. Klyuev
NC JSC Karaganda medical university
Kazakhstan


L. K. Ibrayeva
NC JSC Karaganda medical university
Kazakhstan


D. N. Sheryazdanova
NC JSC Karaganda medical university
Kazakhstan


A. S. Aitken
NC JSC Karaganda medical university
Kazakhstan


A. S. Serikova
NC JSC Karaganda medical university
Kazakhstan


References

1. Исаева Б. Г. Динамика распространенности основных ревматических заболеваний в республике Казахстан за 2012-2016 годы /Б. Г. Исаева, М. М. Сапарбаева, В. Б. Хабижанова // Медицина. - 2018. - №3.-. - С. 17-22.

2. Кондратьева Л. В. Оценка риска развития сахарного диабета 2-го типа у больных ревматоидным артритом c помощью шкалы FINDRISK /Л. В. Кондратьева, Т. В. Попкова, Е. Л. Насонов //Научно-практическая ревматология. - 2017. - №55. - С. 504-508.

3. Calabrese L. The 2015 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis Should Include New Standards for Hepatitis B Screening /L. Calabrese, C. Calabrese, E. Kirchner //Arthritis Care Res (Hoboken). - 2016. - №68 (5). - Р. 723-400.

4. Christensen D. Moving to an A1C-based diagnosis of diabetes has a different impact on prevalence in different ethnic groups /D. Christensen, D. Witte, L. Kaduka //Diabetes Care. -2010.- V. 33. - Р. 580-582.

5. ESC Guidelines on diabetes, prediabetes, and cardiovascular diseases developed in collaboration with the EASD: the Task Force on diabetes, pre-diabetes, and cardiovascular diseases of the European Society of Cardiology (ESC) and developed in collaboration with the European Association for the Study of Diabetes (EASD) // Eur. Heart J. - 2013. - V. 39. - Р. 3035-3087.

6. Iversen M. Physical Activity and Correlates of Physical Activity Participation Over Three Years in Adults With Rheumatoid Arthritis /M. Iversen, M. Frits, von J. Heideken //Arthritis Care Res. (Hoboken). - 2017. - V. 69. - Р.1535-1545.

7. Jiang P. Diabetes mellitus risk factors in rheumatoid arthritis: a systematic review and meta-analysis /P. Jiang, H. Li, X. Li //Clin. Exp. Rheumatol. - 2015. - V. 33. - Р. 115-121.

8. Kreps D. Association of weight loss with improved disease activity in patients with rheumatoid arthritis: A retrospective analysis using electronic medical record data /D. Kreps, F. Halperin, S. Desai //Int. J. Clin. Rheumtol. -2018. - V. 13. - Р. 11-21.

9. Lindstrom J. The diabetes risk score: a practical tool to predict type 2 diabetes risk /J. Lindstrom, J. Tuomilehto //Diabetes Care. -2003. - V. 26. - Р. 725-731.

10. Liu Y. Impact of Obesity on Remission and Disease Activity in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis /Y. Liu, G. Hazlewood, G. Kaplan //Arthritis Care Res (Hoboken). - 2017. - V. 69. - Р. 157-165.

11. Lupoli R. Impact of body weight on the achievement of minimal disease activity in patients with rheumatic diseases: a systematic review and meta-analysis /R. Lupoli, P. Pizzicato, A. Scalera //Arthritis Res. Ther. - 2016. - V. 18. -Р. 297-311.

12. Metsios G. The role of exercise in the management of rheumatoid arthritis /G. Metsios, A. Stavropoulos-Kalinoglou, G. Kitas //Expert Rev. Clin. Immunol. - 2015. - V. 11 (10). - Р. 1121-1130.

13. Nicolau J. Rheumatoid arthritis, insulin resistance, and diabetes /J. Nicolau, T. Lequerre, H. Bacquet //Joint Bone Spine. - 2017. - V. 84 (4). - Р. 411-416.

14. Petersson S. The Mediterranean diet, fish oil supplements and Rheumatoid arthritis outcomes: evidence from clinical trials /S. Petersson, E. Philippou, C. Rodomar //Autoimmun Rev. -2018. - V. 17. - Р. 1105-1114.

15. Philippou E. Are we really what we eat? Nutrition and its role in the onset of rheumatoid arthritis /E. Philippou, E. Nikiphorou //Autoimmun Rev. - 2018. - V. 17. - Р. 1074-1077.

16. Solomon D. Disease activity in rheumatoid arthritis and the risk of cardiovascular events /D. Solomon, G. Reed, J. Kremer // Arthritis Rheumatol. - 2015. - V. 67 (6). - Р. 1449-1455.

17. Suh C. Evaluation of factors affecting the levels of physical activity in patients with rheumatoid arthritis: a cross-sectional study /C. Suh, J. Jung, H. Oh //Clin. Rheumatol. - 2019. -V. 29. - Р. 172-184.

18. Verhoeven F. Physical activity in patients with rheumatoid arthritis /F. Verhoeven, N. Tordi, C. Prati //Joint Bone Spine. - 2016. - V. 83 (3). - Р. 265-270.

19. Zegkos T. Cardiovascular risk in rheumatoid arthritis: assessment, management and next steps /T. Zegkos, G. Kitas //Ther. Adv. Musculoskelet. Dis. - 2016. - V. 8 (3). - Р. 86-101.


Review

For citations:


Shalygina A.A., Turgunova L.G., Klyuev D.A., Ibrayeva L.K., Sheryazdanova D.N., Aitken A.S., Serikova A.S. RISK ASSESSMENT OF THE DEVELOPMENT OF TYPE 2 DIABETES MELLITUS DEPENDING ON THE DEGREE OF ACTIVITY OF RHEUMATOID ARTHRITIS. Medicine and ecology. 2019;(4):57-63. (In Russ.)

Views: 219


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2305-6045 (Print)
ISSN 2305-6053 (Online)