ANALYSIS OF PATTERNS OF CONSUMPTION OF NEW PSYCHOACTIVE SUBSTANCES IN A SAMPLE OF DRUG ADDICTION PATIENTS

Aim of research: is the analysis of patterns of consumption of new psychoactive substances. Materials and methods: a cross-sectional study was conducted among 589 adult patients with experience in the consumption of new psychoactive substances. The scope of the study is drug treatment hospitals of 14 regional centers and two cities of republican significance. Research methods were sociological, clinical, psychopathological and statistical. Results and discussion: The mean age of individuals with experience in NPS consumption was 30.73 years (95% CI: 30.22; 31.3). Men constituted the absolute majority - 512 patients (90.3%). Consumption of synthetic cannabinoids prevailed - 400 cases (67.91%), 289 people (49.07%) indicated samples of synthetic cathinones. The combined intake of cathinones and cannabinoids was demonstrated by 128 people (21.73%). Catinones differed in a variety of routes of administration, including parenteral. More than half of the patients were diagnosed with new psychoactive substances dependence syndrome, including combination with opioids and cannabis. The consumption of synthetic cannabinoids, as well as the combination of several new psychoactive substances, was associated with an increased risk of developing psychotic complications. Conclusions : it is emphasized the need for a systematic assessment of patterns of new psychoactive substances consumption as a key epidemiological indicator, including among those who do not seek inpatient drug treatment.

new psychoactive substances, synthetic cathinones, synthetic cannabinoids, patterns

1. Глава государства подписал поправки по вопросам контроля над оборотом наркотиков https://zakon.kz/4952123-glava-gosudarstva-vnes-popravki-po.html 05.05.2019

2. Национальный отчет о наркоситуации в Республике Казахстан (Наркоситуация в 2017 году) /О. Юсопов, В. Казаков, М. Прилуцкая и др. /Под ред. Т. Забрански, О. Юсопова. - Павлодар, 2018. - С. 160-167.

3. Прилуцкая М. В. Острые эффекты новых психоактивных веществ в клинической практике /М. В. Прилуцкая, С. Н. Молчанов // Наука и здравоохранение. - 2018. - №1. - С. 131-152.

4. Funada D. Changes of clinical symptoms in patients with new psychoactive substance (NPS)-related disorders from fiscal year 2012 to 2014: A study in hospitals specializing in the treatment of addiction /D. Funada, T. Matsumoto, Y. Tanibuchi et al. //Neuropsychopharmacol. Rep. - 2019. - V. 9. - Р. 1-11.

5. High-risk drug use and new psychoactive substances. EMCDDA Rapid Communication / EMCDDA. - Luxembourg, 2017. - 21 p.

6. Not for Human Consumption: A Descriptive Investigation into User Characteristics, Motives, and Consequences Associated with Bath Salt Use /L. Zimmerman, T. M. Kilwein, D. Beyer //J. Psychoactive Drugs.- 2019.- V. 6.- Р. 1-7.

7. Synthetic Cannabinoids: Psychopharmacology, Clinical Aspects, Psychotic Onset /G. Martinotti, R. Santacroce, D. Papanti et al. //CNS Neurol. Disord. Drug. Targets. - 2017. - V. 16 (5). - Р. 567-575.

8. United Nations Office on Drugs and Crime. Early Warning Advisory on New Psychoactive Substances /https:// unodc.org/LSS/Page/ NPS 05.05.2019.

9. United Nations Office on Drugs and Crime. World Drug Report 2018. - Vienna, 2018 -76 p. https://unodc.org/wdr2018/prelaunch/ WDR18_Booklet_3_DRUG_MARKETS.pdf 05.05.2019.