PRESEPSIN SIGNIFICANCE AT INTRAABDOMINAL HYPERTENSION
Abstract
The article presents the results of the study of the effect of intra-abdominal hypertension on the level of highly specific biomarker of gram-negative microflora translocation through the damaged intestinal wall of presepsin in patients with acute surgical pathology of the abdominal cavity. According to the study, an increase in the level of intra-abdominal pressure in patients with acute abdominal pathology leads to an increase in the level of presepsin, causing the development of a preseptic condition that ends with the development of the systemic inflammatory response syndrome, which significantly worsens the severity, course and prognosis of the underlying disease in this category of patients. Early diagnosis of this condition, therefore, early initiation of therapy is crucial in patient survival.
About the Authors
M. M. Mugazov
Karaganda medical university
Kazakhstan
Kazakhstan
D. N. Matyushko
Karaganda medical university
Kazakhstan
Kazakhstan
Ye. A. Ismailov
Karaganda medical university
Kazakhstan
Kazakhstan
Ye. M. Turgunov
Karaganda medical university
Kazakhstan
Kazakhstan
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Review
For citations:
Mugazov M.M., Matyushko D.N., Ismailov Ye.A., Turgunov Ye.M. PRESEPSIN SIGNIFICANCE AT INTRAABDOMINAL HYPERTENSION. Medicine and ecology. 2019;(2):36-40. (In Russ.)
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