Preview

Medicine and ecology

Advanced search

ANALYSIS OF THE EPIDEMIOLOGICAL SITUATION ON WHOOPING COUGH IN THE AKTOBE REGION OF THE REPUBLIC OF KAZAKHSTAN

https://doi.org/10.59598/ME-2305-6053-2025-116-3-48-54

Abstract

Whooping cough, an acute respiratory infection characterized by paroxysmal coughing, remains one of the significant causes of morbidity and mortality among children worldwide, despite the successes of vaccination. According to the World Health Organization, approximately 60 million people are infected with whooping cough each year, of which about 1 million are children under one year old. Alongside high vaccination coverage, many developed countries such as the USA, Australia, and the Netherlands are facing epidemics of whooping cough. Official statistics on morbidity may not reflect the true picture, as only 10-12% of cases are diagnosed.

The aim of this study is to analyze the dynamics of the epidemiological process of whooping cough in the Aktobe region of the Republic of Kazakhstan over the period of 2020-2024. The study utilized statistical data on whooping cough morbidity from the Department of Sanitary and Epidemiological Control for the specified period.

The analysis showed an uneven distribution of whooping cough morbidity, with a marked increase in cases in 2024 compared to previous years. The main factors contributing to the rise in morbidity are the decrease in vaccination coverage and the antivaccine sentiments among the population. According to the Ministry of Health of the Republic of Kazakhstan, 1440 cases of whooping cough were registered at the beginning of 2024, significantly exceeding the figures for 2023.

This study highlights the need to increase vaccination rates and raise public awareness about the risks associated with whooping cough.

About the Authors

Sh. M. Nurmuhamedova
Non-commercial joint stock company «West Kazakhstan Marat Ospanov medical university»
Kazakhstan

Shara Nurmuhamedova 

030000, Aktobe city, Maresyeva str., 68



A. A. Amanshieva
Non-commercial joint stock company «West Kazakhstan Marat Ospanov medical university»
Kazakhstan

030000, Aktobe city, Maresyeva str., 68



S. T. Urazaeva
Non-commercial joint stock company «West Kazakhstan Marat Ospanov medical university»
Kazakhstan

030000, Aktobe city, Maresyeva str., 68



T. B. Begalin
Non-commercial joint stock company «West Kazakhstan Marat Ospanov medical university»
Kazakhstan

030000, Aktobe city, Maresyeva str., 68



A. B. Urazaeva
Non-commercial joint stock company «West Kazakhstan Marat Ospanov medical university»
Kazakhstan

030000, Aktobe city, Maresyeva str., 68



K. Sh. Tusupkalieva
Non-commercial joint stock company «West Kazakhstan Marat Ospanov medical university»
Kazakhstan

030000, Aktobe city, Maresyeva str., 68



G. B. Kumar
Non-commercial joint stock company «West Kazakhstan Marat Ospanov medical university»
Kazakhstan

030000, Aktobe city, Maresyeva str., 68



K. Tashimova
Non-commercial joint stock company «West Kazakhstan Marat Ospanov medical university»
Kazakhstan

030000, Aktobe city, Maresyeva str., 68



References

1. Lapij F. I. Aktual'nost' jeffektivnoj zashhity protiv kokljusha. Zdorov'e rebenka. 2010; 3: 86.

2. Mazankova L. N., Grigor'ev K. I. Kokljush: staraja infekcija, novye problemy. Medicinskaja sestra. 2018; 20 (2): 19-24. https://doi:10.29296/25879979-2018-02-04

3. Ministerstvo zdravoohranenija Respubliki Kazahstan. https://www.gov.kz/memleket/entities/dsm/press/news/details/733043?lang=ru

4. Nikolaeva I. V., Shajhieva G. S. Kokljush na sovremennom jetape. Vestnik sovremennoj klinicheskoj mediciny. 2016; 9 (1): 24-29. https://doi:10.20969/VSKM.2016.9(2).25-29

5. Sizemov A. N., Komeleva E. V. Kokljush: klinika, diagnostika, lechenie. Lechashhij vrach. 2005; 7: 82-87.

6. Tatochenko V. K. Kokljush – nedoupravljaemaja infekcija. Voprosy sovremennoj pediatrii. 2014; 13 (2): 78-82.

7. Bisgard K. M., Pascual F. B., Ehresmann K. R. Infant pertussis: who was the source? Pediatr. Infect. Dis. J. 2004; 23: 985-989.

8. Cherry J. D. Why do pertussis vaccines fail? Pediatrics. 2012; 129: 968-970.

9. Gendrel D., Raymond J. La coqueluche dans le monde. Vacciner l'enfant et l'adulte [Pertussis worldwide. Vaccinating children and adults]. Med. Trop. Sante. Int. 2023; 3(4): 446. https://doi:10.48327/mtsi.v3i4.2023.446

10. Hu Y., Shi W., Meng Q., Yuan L., Gao W., Wang L., Yao K. Detection of Bordetella spp. in children with pertussis-like illness from 2018 to 2024 in China. J. Infect. 2024; 89 (3): 106222. https://doi:10.1016/j.jinf.2024.106222

11. Iozefovich O. V., Harit S. M., Kaplina S. P., Gostev V. V., Sidorenko S. V., Kalinogorskaja O. S., Kvetnaja A. S., Timofeeva E. V., Okuneva M. A. Rasprostranennost' kokljusha u dlitel'no kashljajushhih detej 6 – 17 let, privityh v rannem vozraste AKDS-vakcinoj. Jepidemiologija i vakcinoprofilaktika. 2012; 5: 56-59.

12. Liko J., Robison G. Priming with whole-cell versus acellular pertussis vaccine. N. Engl. J. Med. 2013; 7: 581582.

13. Lobzin, Y. V., Bakhareva N. V. Retrospective Study of the Clinical Epidemiological Characteristics of Pertussis in Infants Prior to Their First Vaccination in the Russian Federation. Infect. Dis. Ther. 2015; 4 (1): 113-123.

14. Noble B. A., Jiudice S. S., Jones J. D., Timbrook T. T. Reemergence of Bordetella parapertussis, United States, 2019-2023. Emerg. Infect. Dis. 2024; 30 (5): 1058-1060. https://doi:10.3201/eid3005.231278

15. Tanne J. H. Whooping cough: Fivefold rise in US cases spells return to pre-pandemic levels. BMJ. 2024; 386: q2114. https://doi.org/10.1136/bmj.q2114

16. World Health Organization.Global and regional immunization profile. http://www.who.int/immunization/monitoring_surveillance/data


Review

For citations:


Nurmuhamedova Sh.M., Amanshieva A.A., Urazaeva S.T., Begalin T.B., Urazaeva A.B., Tusupkalieva K.Sh., Kumar G.B., Tashimova K. ANALYSIS OF THE EPIDEMIOLOGICAL SITUATION ON WHOOPING COUGH IN THE AKTOBE REGION OF THE REPUBLIC OF KAZAKHSTAN. Medicine and ecology. 2025;(3):48-54. (In Russ.) https://doi.org/10.59598/ME-2305-6053-2025-116-3-48-54

Views: 9


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2305-6045 (Print)
ISSN 2305-6053 (Online)