CRYPTOGENIC EOSINOPHILIC MESENTERIC VASCULITIS WITH FATAL OUTCOME: THE POSSIBILITY OF LATENT FLOW OF HYPEREOSINOPHLIC SYNDROME

Idiopathic hypereosinophilic syndrome in practice is defined as prolonged eosinophilia without an established cause and with presence of dysfunction of the organs and systems. In the pathological process, the heart, the central and peripheral nervous system, the lungs and the skin are most often involved. In the presented observation of eosinophilic lesions of the gastrointestinal tract with a lethal outcome, the clinical picture was characterized by typical symptoms of acute appendicitis. After appendectomy, pronounced eosinophilia in the peripheral blood was observed with attachment of neurological disorders and development of multiple organ failure. Histological examination showed pronounced eosinophilic infiltration in the appendix mesentery tissue and small intestine with obliterating angiopathia and chronic ischemia of the intestinal wall. Thus, we believe that in this case there was a latent flow of hypereosinophilic syndrome with a predominant lesion of the gastrointestinal tract.

eosinophilic vasculitis, gastrointestinal tract, neurological disorders

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