medecolМедицина и экологияMedicine and ecology2305-60452305-6053Карагандинский медицинский университет10.59598/ME-2305-6053-2025-114-1-116-125medecol-926Research ArticleКЛИНИЧЕСКАЯ МЕДИЦИНАCLINICAL MEDICINEУлучшение приверженности к терапии пациентов с артериальной гипертензией: рандомизированное контролируемое исследованиеImproving treatment adherence in hypertension patients: a randomised controlled trialМухтархановаД. М.MukhtarkhanovaD. M.

050000, г. Алматы, ул. Айтеке би, 120

050000, Рг. Алматы, ул. Толе Би, 94

050000, Almaty city, Aiteke Bi st., 120,

050000, Almaty city, Tole Bi st., 94

dilyaramukhtarkhan@gmail.comПашимовМ. О.PashimovM. O.

050000, г. Алматы, ул. Айтеке би, 120

050000, Almaty city, Aiteke Bi st., 120

БеркинбаевС. Ф.BerkinbaevS. F.

050000, г. Алматы, ул. Толе Би, 94

050000, Almaty city, Tole Bi st., 94

ДжунусбековаГ. А.DzhunusbekovaG. A.

050000, г. Алматы, ул. Айтеке би, 120,

050000, г. Алматы, ул. Толе Би, 94

050000, Almaty city, Aiteke Bi st., 120,

050000, Almaty city, Tole Bi st., 94

ТундыбаеваМ. К.TundybaevaM. K.

050000, г. Алматы, ул. Айтеке би, 120,

050000, г. Алматы, ул. Толе Би, 94

050000, Almaty city, Aiteke Bi st., 120,

050000, Almaty city, Tole Bi st., 94

МуратовА. Е.MuratovA. E.

050000, г. Алматы, ул. Абылай Хана, 51/53

050000, Almaty city, Abylai Khan st., 51/53

muratov.2@icloud.comДушимоваЗ. Д.DushimovaZ. D.

050000, г. Алматы, ул. Айтеке би, 120,

050040, г. Алматы, ул. пр. аль-Фараби, 71/19

Faculty of Medicine and Healthcare, Al-Farabi Kazakh National University NC JSC 

050000, Almaty city, Aiteke Bi st., 120,

050040, Almaty city, Al-Farabi Ave., 71/19

КултановаЭ. Б.KultanovaE. B.

Эльмира Берикбаевна Култанова – аналитик отдела менеджмента научных исследований

050000, г. Алматы, ул. Айтеке би, 120

Elmira Berikbayevna Kultanova – Research Management Department Analyst, Scientific 

050000, Almaty city, Aiteke Bi st., 120

dsrm.ricid@gmail.comБаглановаЛ. С.BaglanovaL. S.

050000, г. Алматы, ул. Айтеке би, 120,

050000, г. Алматы, ул. Толе Би, 94

050000, Almaty city, Aiteke Bi st., 120

050000, Almaty city, Tole Bi st., 94

АО «Научно-исследовательский институт кардиологии и внутренних болезней»; НАО «КазНМУ имени С. Д. Асфендиярова»КазахстанResearch Institute of Cardiology and Internal Diseases JSC; KazNMU named after S. D. Asfendiyarov NC JSCKazakhstanАО «Научно-исследовательский институт кардиологии и внутренних болезней»КазахстанResearch Institute of Cardiology and Internal Diseases JSCKazakhstanНАО «КазНМУ имени С. Д. Асфендиярова»КазахстанKazNMU named after S. D. Asfendiyarov NC JSCKazakhstanАО «Научно-исследовательский институт кардиологии и внутренних болезней»; НАО «КазНМУ имени С. Д. Асфендиярова»КазахстанResearch Institute of Cardiology and Internal Diseases JSC; KazNMU named after S. D. Asfendiyarov NC JSCKazakhstanНУО «Казахстанско-Российский медицинский университет»КазахстанKazakh-Russian Medical University NDUKazakhstanАО «Научно-исследовательский институт кардиологии и внутренних болезней»; НАО «Казахский национальный университет им. аль-Фараби»КазахстанResearch Institute of Cardiology and Internal Diseases JSC; Faculty of Medicine and Healthcare, Al-Farabi Kazakh National University NC JSCKazakhstan20251605202501116125Copyright © Мухтарханова Д.М., Пашимов М.О., Беркинбаев С.Ф., Джунусбекова Г.А., Тундыбаева М.К., Муратов А.Е., Душимова З.Д., Култанова Э.Б., Багланова Л.С., 20252025Мухтарханова Д.М., Пашимов М.О., Беркинбаев С.Ф., Джунусбекова Г.А., Тундыбаева М.К., Муратов А.Е., Душимова З.Д., Култанова Э.Б., Багланова Л.С.Mukhtarkhanova D.M., Pashimov M.O., Berkinbaev S.F., Dzhunusbekova G.A., Tundybaeva M.K., Muratov A.E., Dushimova Z.D., Kultanova E.B., Baglanova L.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://medecol.qmu.kz/jour/article/view/926Актуальность

Актуальность. Артериальная гипертензия остается одной из ведущих причин сердечно-сосудистых осложнений и смертности во всем мире. Одним из ключевых факторов эффективного контроля артериальной гипертензии является высокая приверженность к медикаментозной терапии, однако ее уровень остается недостаточным. В последние годы активно развиваются цифровые технологии, включая мобильные приложения, предназначенные для повышения приверженности к лечению, однако данные об их эффективности остаются ограниченными.

Цель

Цель. Оценка влияния мобильного приложения «CardioExpert.kz» на приверженность к терапии и контроль артериального давления у пациентов с первичной артериальной гипертензией в условиях рандомизированного контролируемого исследования.

Материалы и методы

Материалы и методы. В исследовании приняли участие 633 пациента с первичной артериальной гипертензией, которые были разделены на 2 группы: контрольную (стандартное лечение) и экспериментальную (использование мобильного приложения). Основными показателями эффективности выступали изменения уровней систолического и диастолического артериального давления, а также уровень приверженности к терапии, оцененный с помощью шкалы MMAS-8.

Результаты и обсуждение

Результаты и обсуждение. Через 1 месяц наблюдения в экспериментальной группе отмечено достоверное снижение систолического (-10,74±20,89 мм рт. ст.) и диастолического (-2,52±12,84 мм рт. ст.) артериального давления по сравнению с контрольной группой (p<0,001). Кроме того, было зафиксировано статистически значимое улучшение приверженности к медикаментозной терапии (p<0,001).

Выводы

Выводы. Использование мобильного приложения продемонстрировало положительное влияние на контроль артериального давления и приверженность к лечению у пациентов с артериальной гипертензией. Однако для оценки долгосрочной эффективности цифровых технологий в управлении гипертонией необходимы дальнейшие исследования с более продолжительным периодом наблюдения.

Background

Background. Arterial hypertension remains one of the leading causes of cardiovascular complications and mortality worldwide. A key factor in effective AH management is high adherence to medication therapy; however, adherence levels remain insufficient. In recent years, digital technologies, including mobile applications designed to enhance treatment adherence, have been actively developing, yet data on their effectiveness remain limited.

Aim

Aim. To evaluate the impact of the mobile application CardioExpert.kz on treatment adherence and blood pressure control in patients with primary hypertension within a randomized controlled trial.

Materials and methods

Materials and methods. The study included 633 patients with primary hypertension who were randomized into two groups: a control group (standard treatment) and an experimental group (using the mobile application). The primary efficacy indicators were changes in systolic and diastolic blood pressure levels, as well as treatment adherence assessed using the MMAS-8 scale. Results and discussion. After 1 month of observation, the experimental group showed a significant reduction in systolic (-10.74±20.89 mmHg) and diastolic blood pressure (-2.52±12.84 mmHg) compared to the control group (р<0.001).

Additionally, a statistically significant improvement in medication adherence was recorded (р<0.001).

Conclusions

Conclusions. The use of a mobile application demonstrated a positive effect on blood pressure control and adherence to treatment in patients with hypertension. However, further studies with a longer follow-up period are needed to assess the long-term effectiveness of digital technologies in hypertension management.

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The authors declare that there are no conflicts of interest present.