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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medecol</journal-id><journal-title-group><journal-title xml:lang="ru">Медицина и экология</journal-title><trans-title-group xml:lang="en"><trans-title>Medicine and ecology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2305-6045</issn><issn pub-type="epub">2305-6053</issn><publisher><publisher-name>Карагандинский медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.59598/ME-2305-6045-2024-113-4-85-90</article-id><article-id custom-type="elpub" pub-id-type="custom">medecol-804</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>Частота обнаружения изолятов Staphylococcus aureus в различных клинических материалах от больных с гнойно-воспалительными заболеваниями в неинфекционных клиниках</article-title><trans-title-group xml:lang="en"><trans-title>Frequency of detection of Staphylococcus aureus isolates in various clinical materials from patients with purulent-inflammatory diseases in non-infectious clinics</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Утегенова</surname><given-names>A. M.</given-names></name><name name-style="western" xml:lang="en"><surname>Utegenova</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Айгуль Маратовна Утегенова – доцент-исследователь кафедры микробиологии и вирусологии</p><p>01000, Рг. Астана, пр. Сарыарка, 33</p></bio><bio xml:lang="en"><p>Aigul Maratovna Utegenova – associate professor-researcher of the department of microbiology and virology</p><p>010000, Astana, Saryarka ave., 33</p></bio><email xlink:type="simple">rectorat@amu.kz</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бисенова</surname><given-names>Н. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Bissenova</surname><given-names>N. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>01000, г. Астана, пр. Абылай Хана, 42</p></bio><bio xml:lang="en"><p>010000, Astana, Abylai Khan ave., 42</p></bio><email xlink:type="simple">national_clinic@nnmc.kz</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дусмагамбетов</surname><given-names>М. У.</given-names></name><name name-style="western" xml:lang="en"><surname>Dusmagambetov</surname><given-names>M. U.</given-names></name></name-alternatives><bio xml:lang="ru"><p>01000, г. Астана, пр. Сарыарка, 33</p></bio><bio xml:lang="en"><p>010000, Astana, Saryarka ave., 33</p></bio><email xlink:type="simple">rectorat@amu.kz</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Урекешов</surname><given-names>Б. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Urekeshov</surname><given-names>B. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>01000, г. Астана, пр. Сарыарка, 33</p></bio><bio xml:lang="en"><p>010000, Astana, Saryarka ave., 33</p></bio><email xlink:type="simple">rectorat@amu.kz</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ильдербаева</surname><given-names>Г. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Ilderbayeva</surname><given-names>G. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>01000, г. Астана, ул. Сатпаева, 2</p></bio><bio xml:lang="en"><p>010000, Astana, Satpayeva str., 2</p></bio><email xlink:type="simple">enu@enu.kz</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">НАО «Медицинский университет Астана»<country>Казахстан</country></aff><aff xml:lang="en">NС JSC «Medical university Astana»<country>Kazakhstan</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">АО «Национальный научный медицинский центр»<country>Казахстан</country></aff><aff xml:lang="en">JSC «National Scientific Medical Center»<country>Kazakhstan</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru">НАО «Евразийский национальный университет им. Л. Н. Гумилева»<country>Казахстан</country></aff><aff xml:lang="en">NJSC «L.N. Gumilyov Eurasian National University»<country>Kazakhstan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>22</day><month>01</month><year>2025</year></pub-date><volume>0</volume><issue>4</issue><fpage>85</fpage><lpage>90</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Утегенова A.M., Бисенова Н.М., Дусмагамбетов М.У., Урекешов Б.С., Ильдербаева Г.О., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Утегенова A.M., Бисенова Н.М., Дусмагамбетов М.У., Урекешов Б.С., Ильдербаева Г.О.</copyright-holder><copyright-holder xml:lang="en">Utegenova A.M., Bissenova N.M., Dusmagambetov M.U., Urekeshov B.S., Ilderbayeva G.O.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medecol.qmu.kz/jour/article/view/804">https://medecol.qmu.kz/jour/article/view/804</self-uri><abstract><p>Цель исследования. Изучение частоты высеваемости Staphylococcus aureus от клинических биоматериалов больных с гнойно-воспалительными заболеваниями за период с 2018 по 2022 год по данным микробиологической лаборатории АО «Национальный научный медицинский центр» (г. Астана).Материалы и методы. Проведено проспективное микробиологическое исследование микробного пейзажа клинических образцов, выделенных у стационарных пациентов с гнойно-воспалительными процессами. Выделение и идентификация штаммов проводились на базе микробиологической лаборатории АО «Национальный научный медицинский центр» (г. Астана).Результаты и обсуждение. По данным микробиологической лаборатории АО «ННМЦ» за период проведенных бактериологических исследований клинических материалов от больных с гнойно-воспалительными заболеваниями различной локализации и других материалов, используемых в лечебном учреждений с 2018 по 2022 год, всего был выделен 961 штамм Staphylococcus aureus. При изучении динамики роста или снижения количества по годам можно отметить, что за все периоды изучения самое значительное увеличение выделения количества Staphylococcus aureus было отмечено только из образцов, взятых из зева, – 57,4%, на втором месте по частоте выделения находится рана – 15%, на третьем месте моча – 6,13%, далее следуют мазок из носа – 3,64% и мокрота – 2,49%.Выводы. Таким образом, одним из доминирующих возбудителей при гнойно-воспалительных заболеваниях является Staphylococcus aureus. Основным клиническим биоматериалом по частоте обнаружения при бактериологическом исследовании образцов, взятых у пациентов неинфекционных клиник с 2018 по 2022 год, был мазок из зева, на долю которого приходилось 57,4%, затем следовали рана (15%) и моча (6,13%). В остальных биоматериалах обнаружение Staphylococcus aureus было незначительным.</p></abstract><trans-abstract xml:lang="en"><p>Aim of the study. To study the frequency of isolation of Staphylococcus aureus from clinical biomaterials of patients with purulent-inflammatory diseases for the period from 2018 to 2022 according to the microbiological laboratory of JSC «National Scientific Medical Center», Astana.Materials and methods. A prospective microbiological study of the microbial landscape isolated from clinical samples of inpatients with purulent-inflammatory processes was carried out. Isolation and identification of strains was carried out on the basis of the microbiological laboratory of JSC «National Scientific Medical Center», Astana.Results and discussion. According to the microbiological laboratory of JSC «National Scientific Medical Center», during the period of bacteriological studies of clinical materials from patients with purulent-inflammatory diseases of various localization and from other materials used in medical institutions, from 2018 to 2022, a total of 961 strains of Staphylococcus aureus were isolated. When studying the dynamics of growth or decrease in the number over the years, it can be noted that for all the periods of study, we noted the most significant increase in the release of the amount of Staphylococcus aureus only from samples taken from the throat – 57.4%. In second place in terms of the frequency of Staphylococcus aureus discharge is a wound – 15%, in third place urine – 6.13%, followed by a nasal smear – 3.64% and sputum – 2.49%, respectively.Conclusion. Thus, one of the dominant pathogens in purulent-inflammatory diseases is Staphylococcus aureus and the main clinical biomaterial according to the frequency of detection during bacteriological examination of patients taken from non-infectious clinics from 2018 to 2022, according to the microbiological laboratory of JSC «NSMC» there was a throat smear, which accounted for 57.4%, then wound – 15% and urine – 6.13%. In the remaining biomaterials, the detection of Staphylococcus aureus was insignificant</p></trans-abstract><kwd-group xml:lang="ru"><kwd>гнойно-воспалительные заболевания</kwd><kwd>Staphylococcus aureus</kwd><kwd>бактериологические исследования</kwd><kwd>биоматериалы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>purulent-inflammatory diseases</kwd><kwd>Staphylococcus aureus</kwd><kwd>bacteriological studies</kwd><kwd>biomaterials</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Davey R. X. The epidemiology of Staphylococcus aureus skin and soft tissue infection in the southern Barkly region of Australia's Northern Territory in 2017 /R. X. Davey, S. Y. C. Tong // Pathology. – 2019. – V. 51 (3). – P. 308-312.</mixed-citation><mixed-citation xml:lang="en">Davey R. X. 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