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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medecol</journal-id><journal-title-group><journal-title xml:lang="ru">Медицина и экология</journal-title><trans-title-group xml:lang="en"><trans-title>Medicine and ecology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2305-6045</issn><issn pub-type="epub">2305-6053</issn><publisher><publisher-name>Карагандинский медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.59598/ME-2305-6045-2024-111-2-93-104</article-id><article-id custom-type="elpub" pub-id-type="custom">medecol-692</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НАБЛЮДЕНИЯ ИЗ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASES</subject></subj-group></article-categories><title-group><article-title>Перипротезная  инфекция сустава после тотального эндопротезирования коленного сустава. Извлеченные уроки: клинический  случай и обзор литературы</article-title><trans-title-group xml:lang="en"><trans-title>Periprosthetic joint  infection after total knee arthroplasty. Lessons learned: a case report and literature review</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Конкаев</surname><given-names>А.</given-names></name><name name-style="western" xml:lang="en"><surname>Konkayev</surname><given-names>A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Айдос Конкаев</p><p>010000, г. Астана, пр. Абылай хана, 15А</p><p>010000, г. Астана, ул. Бейбитшилик, 49а</p></bio><bio xml:lang="en"><p>Aidos Konkayev </p><p>010000, Astana, Abylai-khan avenue, 15A</p><p>010000, Astana, Beibitshilik str., 49A</p></bio><email xlink:type="simple">konkaev@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Азимова</surname><given-names>Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Azimova</surname><given-names>B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>010000, г. Астана, пр. Абылай хана, 15А</p><p>010000, г. Астана, ул. Бейбитшилик, 49а</p></bio><bio xml:lang="en"><p>010000, Astana, Abylai-khan avenue, 15A</p><p>010000, Astana, Beibitshilik str., 49A</p></bio><email xlink:type="simple">info@nscto.kz</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кадралинова</surname><given-names>А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kadralinova</surname><given-names>A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>010000, г. Астана, пр. Абылай хана, 15А</p><p>010000, г. Астана, ул. Бейбитшилик, 49а</p></bio><bio xml:lang="en"><p>010000, Astana, Abylai-khan avenue, 15A</p><p>010000, Astana, Beibitshilik str., 49A</p></bio><email xlink:type="simple">info@nscto.kz</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Елтаева</surname><given-names>А.</given-names></name><name name-style="western" xml:lang="en"><surname>Yeltayeva</surname><given-names>A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>010000, г. Астана, пр. Абылай хана, 15А</p><p>010000, г. Астана, ул. Бейбитшилик, 49а</p></bio><bio xml:lang="en"><p>010000, Astana, Abylai-khan avenue, 15A</p><p>010000, Astana, Beibitshilik str., 49A</p></bio><email xlink:type="simple">info@nscto.kz</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жанарыстан</surname><given-names>Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhanarystan</surname><given-names>N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>010000, г. Астана, ул. Бейбитшилик, 49а</p></bio><bio xml:lang="en"><p>010000, Astana, Beibitshilik str., 49A</p></bio><email xlink:type="simple">rektorat@amu.kz</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Конкаева</surname><given-names>М.</given-names></name><name name-style="western" xml:lang="en"><surname>Konkayeva</surname><given-names>M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>010000, г. Астана, пр. Абылай хана, 15А</p><p>010000, г. Астана, ул. Бейбитшилик, 49а</p></bio><bio xml:lang="en"><p>010000, Astana, Abylai-khan avenue, 15A</p><p>010000, Astana, Beibitshilik str., 49A</p></bio><email xlink:type="simple">info@nscto.kz</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Отделение анестезиологии, реанимации и интенсивной терапии Национального научного центра травматологии и ортопедии им. академика Н. Д. Батпенова; Кафедра анестезиологии и интенсивной терапии №1 НАО «Медицинский университет Астана»<country>Казахстан</country></aff><aff xml:lang="en">Department of Anesthesiology and Intensive Care, National Scientific Center of Traumatology and Orthopedics named after Academician N. D. Batpenov; Department of Anesthesiology and Intensive Care №1, NС JSC «Astana Medical University»<country>Kazakhstan</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Кафедра анестезиологии и интенсивной терапии №1 НАО «Медицинский университет Астана»<country>Казахстан</country></aff><aff xml:lang="en">Department of Anesthesiology and Intensive Care №1, NС JSC «Astana Medical University»<country>Kazakhstan</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru">Отделение анестезиологии, реанимации и интенсивной терапии Национального научного центра травматологии и ортопедии им. академика Н. Д. Батпенова; Кафедра инфекционных болезней и клинической эпидемиологии НАО «Медицинский университет Астана»<country>Казахстан</country></aff><aff xml:lang="en">Department of Anesthesiology and Intensive Care, National Scientific Center of Traumatology and Orthopedics named after Academician N. D. Batpenov; Department of Infectious Diseases and Clinical Epidemiology, NС JSC «Astana Medical University»<country>Kazakhstan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>30</day><month>07</month><year>2024</year></pub-date><volume>0</volume><issue>2</issue><fpage>93</fpage><lpage>104</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Конкаев А., Азимова Б., Кадралинова А., Елтаева А., Жанарыстан Н., Конкаева М., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Конкаев А., Азимова Б., Кадралинова А., Елтаева А., Жанарыстан Н., Конкаева М.</copyright-holder><copyright-holder xml:lang="en">Konkayev A., Azimova B., Kadralinova A., Yeltayeva A., Zhanarystan N., Konkayeva M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medecol.qmu.kz/jour/article/view/692">https://medecol.qmu.kz/jour/article/view/692</self-uri><abstract><sec><title>Введение</title><p>Введение. Увеличение доли стареющего населения, людей с избыточным весом и различными проблемами суставов приводит к увеличению спроса на замену суставов. Поскольку число операций по артропластике суставов продолжает расти, постоянная заболеваемость перипротезными инфекциями суставов подчеркивает необходимость комплексного и развивающегося подхода. Помимо предоперационного периода необходимо учитывать также течение интраоперационного периода, и в большей степени послеоперационного периода, когда происходит развитие перипротезной инфекции. Данный случай свидетельствует о том, что недооценка значения послеоперационного периода и контроля факторов риска может привести к инфекции. Это негативно влияет на экономику из-за роста случаев инвалидазации.</p></sec><sec><title>Клинический случай</title><p>Клинический случай. У пациентки 60 лет после тотального эндопротезирования коленного сустава диагностирована перипротезная инфекция сустава. Преморбидный фон больной отягощался наличием сахарного диабета 2 типа, артериальной гипертензии, вторичной кардиомиопатии, хронической железодефицитной анемии. Одномоментная ревизия эндопротезирования коленного сустава, удаление компонентов протеза, иссечение дегенеративных тканей, длительная антибиотикотерапия, а также реабилитация оказались неэффективными, болевой синдром усилился. В связи с этим пациент госпитализирован на двухэтапную ревизионную операцию, удаление эндопротеза и установку неартикулирующего цементного спейсера с антибиотиком левого коленного сустава.</p></sec><sec><title>Заключение</title><p>Заключение. На основании соответствующего поиска литературы мы полагаем, что некорригированная хроническая железодефицитная анемия в сочетании с неконтролируемым сахарным диабетом как в предоперационном, так и в послеоперационном периоде эндопротезирования суставов может повышать риск развития перипротезной инфекции. Более того, акцентирование внимания пациентов на важности послеоперационного периода и строгий контроль показателей здоровья помогут снизить вероятность повторного протезирования.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. The increasing proportion of the aging population and overweight people with various joint problems leads to an increased demand for joint replacements. As the number of joint arthroplasty surgeries continues to rise, the persistent incidence of periprosthetic joint infections highlights the need for a comprehensive and evolving approach. In addition to the preoperative period, it is also necessary to consider the course of the intraoperative, and to a greater extent the postoperative period, when the development of periprosthetic infection occurs. This case is indicative of the fact that underestimation of the importance of the postoperative period and control of risk factors can lead to the recurrence of infection. This negatively affects the economy due to an increase in the number of disabilities.</p></sec><sec><title>Case presentation</title><p>Case presentation. A 60-year-old female patient was diagnosed with a periprosthetic joint infection following total knee arthroplasty. The patient's premorbid background was aggravated by the presence of type 2 diabetes mellitus, arterial hypertension, secondary cardiomyopathy, and chronic iron-deficiency anemia. Single stage revision of knee arthroplasty, removal of prosthetic components, excision of degenerative tissue, prolonged antibiotic therapy as well as rehabilitation were ineffective, and the pain increased. Therefore, the patient is admitted for the two-stage revision surgery, removal of the endoprosthesis, and installation of a nonarticulating cement spacer of the left knee joint.</p></sec><sec><title>Conclusion</title><p>Conclusion. Through a relevant literature search, we believe that uncorrected chronic iron-deficiency anemia in combination with uncontrolled diabetes mellitus, both in the preoperative and postoperative period for joint replacement, may increase the risk of the development of periprosthetic infection. Moreover, focusing patients' attention on the importance of the postoperative period and strict monitoring of health indicators will help reduce the likelihood of re-prosthetics.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>перипротезная инфекция сустава</kwd><kwd>тотальное эндопротезирование коленного сустава</kwd><kwd>периоперационная анемия</kwd><kwd>факторы риска</kwd><kwd>клинический случай</kwd></kwd-group><kwd-group xml:lang="en"><kwd>periprosthetic joint infection</kwd><kwd>total knee arthroplasty</kwd><kwd>perioperative anemia</kwd><kwd>risk factors</kwd><kwd>a case report</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ahmad M. A. Prevalence and Risk of Infection in Patients with Diabetes following Primary Total Knee Arthroplasty: A Global Systematic Review and Meta-Analysis of 120,754 Knees / M. A. Ahmad, S. Ab Rahman, M. A. Islam //J. Clin. 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