<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medecol</journal-id><journal-title-group><journal-title xml:lang="ru">Медицина и экология</journal-title><trans-title-group xml:lang="en"><trans-title>Medicine and ecology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2305-6045</issn><issn pub-type="epub">2305-6053</issn><publisher><publisher-name>Карагандинский медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.59598/ME-2305-6045-2024-110-1-38-43</article-id><article-id custom-type="elpub" pub-id-type="custom">medecol-649</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>Анализ факторов риска развития внебольничной пневмонии у детей в зависимости от степени тяжести</article-title><trans-title-group xml:lang="en"><trans-title>Analysis of risk factors for the development of community acquisited pneumonia in children depending on the degree of severity</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ахаева</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Akhayeva</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ардак Секеновна Ахаева – ассоцированный профессор,</p><p>100008, г. Караганда, ул. Гоголя, 40.</p></bio><bio xml:lang="en"><p>Ardak Sekenovna Akhayeva - AssociateProfessor,</p><p>40,Gogol str., Karaganda, 100008.</p></bio><email xlink:type="simple">a.ahaeva@qmu.kz</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тукбекова</surname><given-names>Б. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Tukbekova</surname><given-names>B. T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>100008, г. Караганда, ул. Гоголя, 40.</p></bio><bio xml:lang="en"><p>40,Gogol str., Karaganda, 100008.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кысабекова</surname><given-names>А. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Kysabekova</surname><given-names>A. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>100008, г. Караганда, ул. Гоголя, 40.</p></bio><bio xml:lang="en"><p>40,Gogol str., Karaganda, 100008.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Скосарев</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Skosarev</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>100008, г. Караганда, ул. Гоголя, 40.</p></bio><bio xml:lang="en"><p>40,Gogol str., Karaganda, 100008.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жупенова</surname><given-names>Д. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhupenova</surname><given-names>D. Ye.</given-names></name></name-alternatives><bio xml:lang="ru"><p>100008, г. Караганда, ул. Гоголя, 40.</p></bio><bio xml:lang="en"><p>40,Gogol str., Karaganda, 100008.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Турлыбекова</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Turlybekova</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>100008, г. Караганда, ул. Гоголя, 40.</p></bio><bio xml:lang="en"><p>40,Gogol str., Karaganda, 100008.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кенжетаева</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kenzhetayeva</surname><given-names>T. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>100008, г. Караганда, ул. Гоголя, 40.</p></bio><bio xml:lang="en"><p>40,Gogol str., Karaganda, 100008.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жанпейсова</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhanpeisova</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>100008, г. Караганда, ул. Гоголя, 40.</p></bio><bio xml:lang="en"><p>40,Gogol str., Karaganda, 100008.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ахметова</surname><given-names>Г. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Akhmetova</surname><given-names>G. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Караганда, ул. К. Либкнехта, 106.</p></bio><bio xml:lang="en"><p>106, K. Liebknecht str., Karaganda. </p></bio><email xlink:type="simple">kgkp_52@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Кафедра педиатрии и неонатологии, НАО «Медицинский университет Караганды»<country>Казахстан</country></aff><aff xml:lang="en">Department of Pediatrics and Neonatology of Karaganda Medical University NC JSC<country>Kazakhstan</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">«Многопрофильная детская больница города Караганды» Управления здравоохранения Карагандинской области<country>Казахстан</country></aff><aff xml:lang="en">Multidisciplinary Children's Hospital of Karaganda City, Department of Health of Karaganda Region<country>Kazakhstan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>13</day><month>06</month><year>2024</year></pub-date><volume>0</volume><issue>1</issue><fpage>38</fpage><lpage>43</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ахаева А.С., Тукбекова Б.Т., Кысабекова А.Б., Скосарев И.А., Жупенова Д.Е., Турлыбекова С.А., Кенжетаева Т.А., Жанпейсова А.А., Ахметова Г.Б., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Ахаева А.С., Тукбекова Б.Т., Кысабекова А.Б., Скосарев И.А., Жупенова Д.Е., Турлыбекова С.А., Кенжетаева Т.А., Жанпейсова А.А., Ахметова Г.Б.</copyright-holder><copyright-holder xml:lang="en">Akhayeva A.S., Tukbekova B.T., Kysabekova A.B., Skosarev I.A., Zhupenova D.Y., Turlybekova S.A., Kenzhetayeva T.A., Zhanpeisova A.A., Akhmetova G.B.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medecol.qmu.kz/jour/article/view/649">https://medecol.qmu.kz/jour/article/view/649</self-uri><abstract><sec><title>Цель работы</title><p>Цель работы. Исследование роли основных факторов риска внебольничной пневмонии у детей.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Исследование проведено среди 136 детей с пневмонией вне стационара в возрасте от 3 до 14 лет. Среди них 37% составляли мальчики, находящиеся на лечении в специализированном отделении. В ходе исследования все дети были разделены на группы по степени тяжести (I, II и III группы). Диагноз верифицировался на основании клинико-анамнестических и лабораторно-фундаментальных данных согласно диагностическому протоколу Республики Казахстан. Статистический анализ полученных данных проводили стандартными методами вариационной статистики, оценивая корректность различий.</p></sec><sec><title>Результаты и обсуждение</title><p>Результаты и обсуждение. Наиболее важными факторами риска у обследованных детей явились факторы риска: повышение артериального давления во время беременности (59,4+4,21); чрезмерная работа матери во время беременности (48,4+3,17); раннее искусственное вскармливание на первом году жизни (61,5+4,93); проявления белково-энергетической недостаточности на первом году жизни (53,9+3,53), соответственно, несоответствие веса и роста на первом году жизни (33,9+3,11) и рахит на первом году жизни ребенка и факторы пневмонии ( 46,9+4,11; 40,5+3,21).</p></sec><sec><title>Заключение</title><p>Заключение. В ходе исследования была определена различная степень встречаемости факторов риска в зависимости от тяжести внебольничной пневмонии у обследованных детей. Полученные результаты свидетельствуют о необходимости учитывать факторы риска для определения тяжести заболевания в качестве дополнительного критерия.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim of the study</title><p>Aim of the study. Study of the role of the main risk factors for community-acquired pneumonia in children.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The study was conducted among 136 children with pneumonia out of hospital, aged 3 to 14 years. Among them, 37% were boys undergoing treatment in a specialized department. During the study, all children were divided into groups according to severity (groups I, II and III). The diagnosis was verified on the basis of clinical, anamnestic and laboratory fundamental data in accordance with the diagnostic protocol of the Republic of Kazakhstan. Statistical analysis of the obtained data was carried out using standard methods of variation statistics, assessing the correctness of the differences.</p></sec><sec><title>Results and discussion</title><p>Results and discussion. The most important risk factors in the examined children were: increased blood pressure during pregnancy (59.4+4.21); excessive work of the mother during pregnancy (48.4+3.17); early artificial feeding in the 1st year of life (61.5+4.93); manifestations of protein-energy deficiency in the 1st year of life (53.9 + 3.53), respectively, discrepancy between weight and height in the 1st year of life (33.9 + 3.11) and rickets in the 1st year of life child and pneumonia factors (46.9+4.11; 40.5+3.21).</p></sec><sec><title>Conclusion</title><p>Conclusion. The study determined the varying degrees of occurrence of risk factors depending on the severity of community-acquired pneumonia in the examined children. The results obtained indicate the need to take into account risk factors to determine the severity of the disease as an additional criterion.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>дети</kwd><kwd>пневмония</kwd><kwd>факторы риска</kwd></kwd-group><kwd-group xml:lang="en"><kwd>children</kwd><kwd>pneumonia</kwd><kwd>risk factors</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">McAllister D. A. Global, regional, and national estimates of pneumonia morbidity and mortality in children younger than 5 years between 2000 and 2015: a systematic analysis /D. A. McAllister, L. Liu, T. Shi //Lancet Glob. Health. – 2019. – V. 7 (1). – e47-e57. doi: 10.1016/S2214-109X(18)30408-X. Epub 2018 Nov 26. PMID: 30497986; PMCID: PMC6293057.</mixed-citation><mixed-citation xml:lang="en">McAllister D. A. Global, regional, and national estimates of pneumonia morbidity and mortality in children younger than 5 years between 2000 and 2015: a systematic analysis /D. A. McAllister, L. Liu, T. Shi //Lancet Glob. Health. – 2019. – V. 7 (1). – e47-e57. doi: 10.1016/S2214-109X(18)30408-X. Epub 2018 Nov 26. PMID: 30497986; PMCID: PMC6293057.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Pettigrew M. M. Association of sputum microbiota profiles with severity of communityacquired pneumonia in children /M. M. Pettigrew, J. F. Gent, Y. Kong //BMC Infect. Dis. – 2016. – V. 8. – P. 317. doi: 10.1186/s12879-016-1670-4. PMID: 27391033; PMCID: PMC4939047.</mixed-citation><mixed-citation xml:lang="en">Pettigrew M. M. Association of sputum microbiota profiles with severity of communityacquired pneumonia in children /M. M. Pettigrew, J. F. Gent, Y. Kong //BMC Infect. Dis. – 2016. – V. 8. – P. 317. doi: 10.1186/s12879-016-1670-4. PMID: 27391033; PMCID: PMC4939047.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Qian J. Analysis of clinical features and risk factors of necrotizing pneumonia in children /J. Qian, Y. J.Wei, Y. J. Cheng //Beijing Da Xue Xue Bao Yi Xue Ban. – 2022. – V. 54 (3). – P. 541-547. doi: 10.19723/j.issn.1671-167X.2022.03.021. PMID: 35701133; PMCID: PMC9197706.</mixed-citation><mixed-citation xml:lang="en">Qian J. Analysis of clinical features and risk factors of necrotizing pneumonia in children /J. Qian, Y. J.Wei, Y. J. Cheng //Beijing Da Xue Xue Bao Yi Xue Ban. – 2022. – V. 54 (3). – P. 541-547. doi: 10.19723/j.issn.1671-167X.2022.03.021. PMID: 35701133; PMCID: PMC9197706.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Taksande A. M. Risk factors for acute respiratory infection (ARI) in under-fives in a rural hospital of Central India /A. M. Taksande, M. J. Yeole //Pediatr. Neonatal Individ. Med. – 2016. – V. 5 (1). – e050105.</mixed-citation><mixed-citation xml:lang="en">Taksande A. M. Risk factors for acute respiratory infection (ARI) in under-fives in a rural hospital of Central India /A. M. Taksande, M. J. Yeole //Pediatr. Neonatal Individ. Med. – 2016. – V. 5 (1). – e050105.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Teshome A. Prevalence of pneumonia and factors associated among children 2-59 months old in Wondo Genet district, Sidama zone, SNNPR, Ethiopia //Curr. Pediatr. Res. – 2017. – V. 21(1). – P. 19-25.</mixed-citation><mixed-citation xml:lang="en">Teshome A. Prevalence of pneumonia and factors associated among children 2-59 months old in Wondo Genet district, Sidama zone, SNNPR, Ethiopia //Curr. Pediatr. Res. – 2017. – V. 21(1). – P. 19-25.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Time-to-recovery from severe pneumonia and its determinants among children under-five admitted to university of Gondar Comprehensive Specialized Hospital in Ethiopia: a retrospective follow-up study; 2015-2020 //Pediatr. Health Med. Ther. – 2021. – V. 12. – P. 189-196.</mixed-citation><mixed-citation xml:lang="en">Time-to-recovery from severe pneumonia and its determinants among children under-five admitted to university of Gondar Comprehensive Specialized Hospital in Ethiopia: a retrospective follow-up study; 2015-2020 //Pediatr. Health Med. Ther. – 2021. – V. 12. – P. 189-196.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Wang H. Efficacy and safety of reduning injection combined with azithromycin in the treatment of mycoplasma pneumonia among children: A systematic review and meta-analysis /H. Wang, M. Zhao, S. Liu //Phytomedicine. – 2022. – V. 106. – 154402. doi: 10.1016/j.phymed.2022.154402. Epub 2022 Aug 21. PMID: 36029644.</mixed-citation><mixed-citation xml:lang="en">Wang H. Efficacy and safety of reduning injection combined with azithromycin in the treatment of mycoplasma pneumonia among children: A systematic review and meta-analysis /H. Wang, M. Zhao, S. Liu //Phytomedicine. – 2022. – V. 106. – 154402. doi: 10.1016/j.phymed.2022.154402. Epub 2022 Aug 21. PMID: 36029644.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Zhai Y. Y. An analysis of 20 clinical cases of refractory mycoplasma pneumonia in children / Y. Y. Zhai, S. Z. Wu, Y. Yang //Ann. Palliat. Med. – 2020. – V. 9 (5). – P. 2592-2599. doi: 10.21037/apm19-497. Epub 2020 Sep 7. PMID: 32921097.</mixed-citation><mixed-citation xml:lang="en">Zhai Y. Y. An analysis of 20 clinical cases of refractory mycoplasma pneumonia in children / Y. Y. Zhai, S. Z. Wu, Y. Yang //Ann. Palliat. Med. – 2020. – V. 9 (5). – P. 2592-2599. doi: 10.21037/apm19-497. Epub 2020 Sep 7. PMID: 32921097.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
