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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medecol</journal-id><journal-title-group><journal-title xml:lang="ru">Медицина и экология</journal-title><trans-title-group xml:lang="en"><trans-title>Medicine and ecology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2305-6045</issn><issn pub-type="epub">2305-6053</issn><publisher><publisher-name>Карагандинский медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">medecol-63</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>НЕЙТРОФИЛ-ЖЕЛАТИНОЗА-АССОЦИИРОВАННЫЙ ЛИПОКАЛИН В ПРОГНОЗИРОВАНИИ ПОВРЕЖДЕНИЯ ПОЧЕК У ДЕТЕЙ</article-title><trans-title-group xml:lang="en"><trans-title>NEUTROPHIL GEULATINASE-ASSOCIATED IPOCAIN IN PREDICTING KIDNEY INJURY IN CHILDREN</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дильдабекова</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Dudabekova</surname><given-names>A. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Басишвили</surname><given-names>Н. З.</given-names></name><name name-style="western" xml:lang="en"><surname>Basishvili</surname><given-names>N. Z.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Абеуова</surname><given-names>Б. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Abeuova</surname><given-names>B. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бегайдарова</surname><given-names>Р. Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Begaydarova</surname><given-names>R. Kh.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жумаканова</surname><given-names>К. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhumakanova</surname><given-names>K. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Карагандинский государственный медицинский университет<country>Казахстан</country></aff><aff xml:lang="en">Karaganda state medical university<country>Kazakhstan</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Медицинский университет Давида Твилдиани<country>Казахстан</country></aff><aff xml:lang="en">David Twiidiani Medical University<country>Kazakhstan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>07</day><month>09</month><year>2021</year></pub-date><volume>0</volume><issue>3</issue><fpage>57</fpage><lpage>59</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Дильдабекова А.С., Басишвили Н.З., Абеуова Б.А., Бегайдарова Р.Х., Жумаканова К.С., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Дильдабекова А.С., Басишвили Н.З., Абеуова Б.А., Бегайдарова Р.Х., Жумаканова К.С.</copyright-holder><copyright-holder xml:lang="en">Dudabekova A.S., Basishvili N.Z., Abeuova B.A., Begaydarova R.K., Zhumakanova K.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medecol.qmu.kz/jour/article/view/63">https://medecol.qmu.kz/jour/article/view/63</self-uri><abstract><p>Цель. Оценить возможность NGAL в моче в прогнозировании повреждения почек у детей раннего возраста с острыми кишечными инфекциями. Материалы и методы. Обследованы 94 ребенка с ОКИ. Возраст пациентов до 3 лет. Для исследования функции почек наряду с общеклиническими исследованиями определяли NGAL в моче. Результаты. Выявлено, что у детей с ОКИ чем выше степень эксикоза, тем выше уровни NGAL в моче у детей. Выводы. Определение концентрации NGAL в сравнении с креатинином сыворотки, может позволит выявить раннее нарушение функции почек у детей.</p></abstract><trans-abstract xml:lang="en"><p>Aim. Assess the possibility of NGAL in the urine in predicting kidney injury in children with acute intestinal infection. Materials and methods. The study involved 94 children with acute intestinal infection. The age of children up to 3 years. For the study of renal function along with clinical tests measured NGAL. Results. It was revealed that in children with acute intestinal infections the higher the degree of excoxicosis, the higher the levels of NGAL in urine in children. Conclusions. The determination of the concentration of NGAL in comparison with serum creatinine, may reveal early impairment of renal function in children.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>нейтрофил-желатиноза-ассоциированный липокалин</kwd><kwd>повреждение почек</kwd><kwd>бүйрек зақымдалуы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>neutrophil gelatinase-associated lipocalin</kwd><kwd>kidney injury</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Mаrtensson J. I. The rise and fall of NGAL in acute kidney injury /J. I. Mаrtensson, R. Bellomo //Blood. Purif. - 2014. - V. 37 (4). - Р. 304-310.</mixed-citation><mixed-citation xml:lang="en">Mаrtensson J. I. 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