medecolМедицина и экологияMedicine and ecology2305-60452305-6053Карагандинский медицинский университет10.59598/ME-2305-6045-2023-109-4-25-34medecol-434Research ArticleОБЗОРЫ ЛИТЕРАТУРЫLITERATURE REVIEWSХимические вещества, разрушающие эндокринную систему, их источники, проблемы со здоровьем и биодеградация с использованием лакказыEndocrine-disrupting chemicals (EDCs), their sources, health concerns and biodegradation of EDCs using laccaseСингхДж.SinghJ.

Джагдип Сингх – ассоциированный профессор

Раджастхан, Видьянагри, дорога Джхунджхуну Бисау, Чудела, округ Джхунджхуну

Jagdeep Singh – Assistant Professor

Rajasthan, Vidyanagri, Jhunjhunu Bisau Road, Chudela, District – Jhunjhunu

jagdeeprajendra@gmail.comУниверситет Шри Джагдишпрасада Джабармала ТибревалаИндияShri Jagdishprasad Jhabarmal Tibrewala UniversityIndia202326122023042534Copyright © Сингх Д., 20232023Сингх Д.Singh J.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://medecol.qmu.kz/jour/article/view/434

В настоящее время присутствие в окружающей среде химических веществ, разрушающих эндокринную систему, является важным фактором, влияющим на функционирование экологических систем и здоровье отдельных людей. Химические вещества, разрушающие эндокринную систему, присутствуют в широком спектре потребительских товаров и нарушают функционирование гормонов, вызывая проблемы, связанные с ростом и развитием, у людей, подвергшихся воздействию. Лакказа – это медьсодержащий фермент, который продемонстрировал свой потенциал в процессе разложения химических веществ, разрушающих эндокринную систему. Микробиологическое производство лакказы требует богатого источника лигнина наряду с целлюлозой, гемицеллюлозой и другими белками. Таким образом, отходы, богатые лигноцеллюлозой, могут рассматриваться как субстраты для производства лакказы с использованием микроорганизмов. В статье представлен обзор химических веществ, разрушающие эндокринную систему, изучена роль лакказы в биодеградации химических веществ, разрушающих эндокринную систему.

At present, the presence of endocrine disruptor chemicals in the environment are important factors that are affecting the functioning of environmental systems and the health of individuals. Endocrine-disrupting chemicals are present in a wide variety of consumer products and interfere with the functioning of hormones and causing growth and development-related problems in exposed individuals. Laccase is a copper-containing enzyme that has shown its potential to degrade Endocrine-disrupting chemicals. The microbial production of laccase requires a rich source of lignin along with cellulose, hemicelluloses, and other proteins. Thus, lignocelluloses rich wastes may be considered as good substrates for the production of laccase using microorganisms. In this article, we have discusses the fate of endocrine disruptors, and role of laccase in the biodegradation of endocrine disruptors.

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The authors declare that there are no conflicts of interest present.