medecolМедицина и экологияMedicine and ecology2305-60452305-6053Карагандинский медицинский университетmedecol-392Research ArticleЭКОЛОГИЯ И ГИГИЕНАECOLOGY AND HYGIENEОсобенности биоэлементного статуса детей и подростков, проживающих в нефтегазоносных регионахFeatures of the bioelement status of children and adolescents living in oil and gas regionsЖумалинаА.ZhumalinaAk.

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ТусупкалиевБ. Т.TusupkalievB. T.

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КимИ. С.KimI. S.

Ирина Сергеевна Ким – ассистент кафедры детских  болезней №1 с неонатологией, тел.: +77015281354

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Irina Sergeevna Kim – assistant of the department of pediatric diseases №1 with neonatology

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irina.kim.90@mail.ruЖарлыкасиноваМ. Б.ZharlykasinovaM. B.

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Западно-Казахстанский медицинский университет имени Марата ОспановаКазахстанWest Kazakhstan Medical University named after Marat OspanovKazakhstan202104062023032028Copyright © Жумалина А., Тусупкалиев Б.Т., Ким И.С., Жарлыкасинова М.Б., 20232023Жумалина А., Тусупкалиев Б.Т., Ким И.С., Жарлыкасинова М.Б.Zhumalina A., Tusupkaliev B.T., Kim I.S., Zharlykasinova M.B.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://medecol.qmu.kz/jour/article/view/392

В условиях интенсивной разработки газовых месторождений вопросы экологической безопасности приобретают все большее значение. Высокие темпы добычи газа и рост его химической переработки превратили предприятия газовой отрасли в мощный источник загрязнения окружающей среды, что представляет реальную угрозу для здоровья населения, способствует росту заболеваемости и экологически обусловленных патологических состояний. Цель исследования - изучение минерализации костной ткани у детей с разным уровнем физического развития, определение вариантов физического развития, которые могли бы являться критериями отнесения детей к группам повышенного риска развития остеопении и показаниями к проведению углубленного лабораторного и инструментального обследования. Обследовано 519 подростков в возрасте 14-17 лет, из них 349 проживали в нефтегазоносном регионе и 170- контрольная группа. Проводились антропометрия и биохимическое обследование крови для определения показателей костного обмена (остеокальцин, кальций, фосфор, ПТГ, P1NP,b-Сrosslaps). В результате было выявлено: что физическое развитие и показатели костного метаболизма у детей нефтегазоносного региона ниже по сравнению с контрольной группой. Показатель, характеризующий соотношение процессов P1NP/b-Сrosslaps, костного ремоделирования оказался практически в 2 раза ниже у детей основной группы (р = 0,039), что может свидетельствовать об относительном превалировании резорбтивных процессов над синтетическими в костной ткани у детей нефтегазоносного региона.

In the context of intensive development of gas industry, environmental safety issues are becoming increasingly important. The high rates of gas production and the growth of its chemical processing have turned gas industry enterprises into a powerful source of environmental pollution, which poses a real threat to public health, contributes to an increase in morbidity and ecologically caused pathological conditions. The aim of the study was to study the mineralization of bone tissue in children with different levels of physical development, to determine the options for physical development, which could be the criteria for classifying children into groups at increased risk of osteopenia and indications for in-depth laboratory and instrumental examination. 519 adolescents aged 14-17 years were examined, of which 349 lived in the oil and gas region and 170 were the control group. Anthropometry and biochemical blood examination were performed to determine the parameters of bone metabolism (osteocalcin, calcium, phosphorus, PTH, P1NP, bCrosslaps). As a result, it was revealed that the physical development and indicators of bone metabolism in children of the oil and gas region are lower than in the control group. The indicator characterizing the ratio of P1NP/b-Crosslaps processes, bone remodeling was almost 2 times lower in children of the main group (p=0.039), which may indicate a relative prevalence of resorptive processes over synthetic in bone tissue in children of the oil and gas region.

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The authors declare that there are no conflicts of interest present.