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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medecol</journal-id><journal-title-group><journal-title xml:lang="ru">Медицина и экология</journal-title><trans-title-group xml:lang="en"><trans-title>Medicine and ecology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2305-6045</issn><issn pub-type="epub">2305-6053</issn><publisher><publisher-name>Карагандинский медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">medecol-356</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ТЕОРЕТИЧЕСКАЯ И ЭКСПЕРИМЕНТАЛЬНАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>THEORETICAL AND EXPERIMENTAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>Исследование антиоксидантной и антирадикальной активности сухого экстракта Phlomoides tuberosa (L.) Moench. in vitro</article-title><trans-title-group xml:lang="en"><trans-title>Study of antioxidant and antiradical activity of dry extract of Phlomoides tuberosa (L.) Moench. in vitro</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жолдасбаев</surname><given-names>М. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Zholdasayev</surname><given-names>M. Y.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Муса Еркенулы Жолдасбаев – пост-докторант Школы фармации, тел.: +77081500109</p><p>Караганда</p></bio><bio xml:lang="en"><p>Karaganda</p></bio><email xlink:type="simple">Zholdasbaev@qmu.kz</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нартайлулы</surname><given-names>К. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Nartailuly</surname><given-names>K. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Караганда</p></bio><bio xml:lang="en"><p>Karaganda</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Атажанова</surname><given-names>Г. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Atazhanova</surname><given-names>G. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Караганда</p></bio><bio xml:lang="en"><p>Karaganda</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лосева</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Losseva</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Караганда</p></bio><bio xml:lang="en"><p>Karaganda</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Медицинский университет Караганды<country>Казахстан</country></aff><aff xml:lang="en">Karaganda medical university<country>Kazakhstan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>02</day><month>06</month><year>2023</year></pub-date><volume>0</volume><issue>2</issue><fpage>53</fpage><lpage>56</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Жолдасбаев М.Е., Нартайлулы К.Е., Атажанова Г.А., Лосева И.В., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Жолдасбаев М.Е., Нартайлулы К.Е., Атажанова Г.А., Лосева И.В.</copyright-holder><copyright-holder xml:lang="en">Zholdasayev M.Y., Nartailuly K.E., Atazhanova G.A., Losseva I.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medecol.qmu.kz/jour/article/view/356">https://medecol.qmu.kz/jour/article/view/356</self-uri><abstract><p>Цель нашей работы заключалась в исследовании антирадикальной и антиоксидантной активности ультразвуковых экстрактов зопника клубненосного (Phlómis tuberosa L), произрастающего на территории Карагандинской области. Водный экстракт Phlómis tuberosa, полученный в условиях ультразвуковой кавитации, обладает выраженной антирадикальной активностью, все другие образцы проявили низкую антирадикальную и антиоксидантную активность. Сумма экстрактивных веществ водного ультразвукового экстракта растения Phlómis tuberosa подчеркивает его терапевтическую значимость и позволяет использовать данный экстракт в дальнейшем для создания лекарственных средств на его основе.</p></abstract><trans-abstract xml:lang="en"><p>The purpose of our work was to study the antiradical and antioxidant activity of ultrasonic extracts of tuberous zopnik (Phlómis tuberosa L), growing on the territory of the Karaganda region. The aqueous extract of Phlómis tuberosa obtained under ultrasonic cavitation has pronounced antiradical activity, all other samples showed low antiradical and antioxidant activity. The sum of extractive substances of the aqueous ultrasonic extract of the Phlómis tuberosa plant emphasizes its therapeutic significance and allows using this extract in the future to create medicines based on it.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>антиоксидантная активность</kwd><kwd>антирадикальная активность</kwd><kwd>Phlómis tuberosa (L) Moench.</kwd><kwd>ультразвуковая экстракция</kwd></kwd-group><kwd-group xml:lang="en"><kwd>antioxidant activity</kwd><kwd>anti-radical activity</kwd><kwd>Phlomoides tuberosa (l.) Moench.</kwd><kwd>ultrasonic extraction</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Kirillov, V.U. Chemical Composition of Essential Oil from Aerial Parts of Phlomis tuberosa L. Growing Wild in Northern Kazakhstan /V.U. 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