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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medecol</journal-id><journal-title-group><journal-title xml:lang="ru">Медицина и экология</journal-title><trans-title-group xml:lang="en"><trans-title>Medicine and ecology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2305-6045</issn><issn pub-type="epub">2305-6053</issn><publisher><publisher-name>Карагандинский медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">medecol-270</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>КОМБИНИРОВАННОЕ ЛЕЧЕНИЕ РАКА СРЕДНЕ-ГРУДНОГО И НИЖНЕ-ГРУДНОГО ОТДЕЛОВ ПИЩЕВОДА</article-title><trans-title-group xml:lang="en"><trans-title>COMBINED TREATMENT OF MID-TECTORAL AND LOWER-TECTORAL OESOPHAGUS CANCER</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Букенов</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Bukenov</surname><given-names>A. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Капезова</surname><given-names>М. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kapezova</surname><given-names>M. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жумабекова</surname><given-names>А. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhumabekova</surname><given-names>A. B.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Омар</surname><given-names>Ә. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Omar</surname><given-names>A. T.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Айдарбекова</surname><given-names>А. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Aidarbekova</surname><given-names>A. K.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баянова</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Bayanova</surname><given-names>N. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Касимова</surname><given-names>Ю. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Kasimova</surname><given-names>Yu. R.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Медицинский университет Караганды<country>Казахстан</country></aff><aff xml:lang="en">Karaganda medical university<country>Kazakhstan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>11</day><month>10</month><year>2021</year></pub-date><volume>0</volume><issue>2</issue><fpage>68</fpage><lpage>74</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Букенов А.М., Капезова М.С., Жумабекова А.Б., Омар Ә.Т., Айдарбекова А.К., Баянова Н.В., Касимова Ю.Р., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Букенов А.М., Капезова М.С., Жумабекова А.Б., Омар Ә.Т., Айдарбекова А.К., Баянова Н.В., Касимова Ю.Р.</copyright-holder><copyright-holder xml:lang="en">Bukenov A.M., Kapezova M.S., Zhumabekova A.B., Omar A.T., Aidarbekova A.K., Bayanova N.V., Kasimova Y.R.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medecol.qmu.kz/jour/article/view/270">https://medecol.qmu.kz/jour/article/view/270</self-uri><abstract><p>В статье анализированы результаты комбинированного лечения 366 больных раком средне-грудного и нижне-грудного отделов пищевода. Среди пациентов преобладали больные с T3N0M0 (59,6%) и T4аN0M0, T3N1M0 (16,9%). Регионарные метастазы были выявлены в 25,7% случаев. С учетом степени распространенности процесса проведены: хирургическое лечение (45,4%), радикальная лучевая терапия (41,5%), комбинированное лечение (13,1%). Анализ отдаленных результатов показал, что общая выживаемость в зависимости от способа лечения составила при хирургическом лечении 26,5%, при комбинированном лечении - 17,6%. Многофакторный анализ отдаленных результатов оказался достаточно высоким при хирургическом лечении (р&lt;0,05).</p></abstract><trans-abstract xml:lang="en"><p>The article analyzes the results of combined treatment of 366 patients with cancer of the middle thoracic and lower thoracic esophagus. Patients with T3N0M0 (59.6%) and T4aN0M0, T3N1M0 (16.9%) prevailed among the patients. Regional metastases were detected in 25.7% of cases. Taking into account the extent of the process, the following were performed: surgical treatment (45.4%), radical radiation therapy (41.5%), combined treatment (13.1%). Analysis of long-term results showed that overall survival, depending on the method of treatment, was 26.5% with surgical treatment, and 17.6% with combined treatment. Multivariate analysis of long-term results was high enough for surgical treatment (p &lt;0.05).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>рак пищевода</kwd><kwd>хирургическое лечение</kwd><kwd>метастазы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>esophageal cancer</kwd><kwd>surgical treatment</kwd><kwd>metastases</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Давыдов М. И. Эволюция онкохирургии и ее перспективы. 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