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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medecol</journal-id><journal-title-group><journal-title xml:lang="ru">Медицина и экология</journal-title><trans-title-group xml:lang="en"><trans-title>Medicine and ecology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2305-6045</issn><issn pub-type="epub">2305-6053</issn><publisher><publisher-name>Карагандинский медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">medecol-269</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>МИКРОБИОЛОГИЧЕСКОЕ ИССЛЕДОВАНИЕ РЕСПИРАТОРНОГО ТРАКТА АМБУЛАТОРНЫХ ПАЦИЕНТОВ</article-title><trans-title-group xml:lang="en"><trans-title>MICROBIOLOGICAL INVESTIGATION OF OUTPATIENTS'RESPIRATORY TRACT</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бисенова</surname><given-names>Н. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Bissenova</surname><given-names>N. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тулеубаева</surname><given-names>Э. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Tuleubyeva</surname><given-names>Ye. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трофимчук</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Trofimchuk</surname><given-names>Y. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ергалиева</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Yergsliyeva</surname><given-names>A. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Таханова</surname><given-names>Р. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Takhanova</surname><given-names>R. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Айгожина</surname><given-names>Б. Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Aigozhina</surname><given-names>B. H.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жидебаева</surname><given-names>К. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhidebayeva</surname><given-names>K. K.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">АО «Национальный научный медицинский центр»<country>Казахстан</country></aff><aff xml:lang="en">JSC National Scientific Medical Research Center<country>Kazakhstan</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">ГКП на ПХВ «Городская поликлиника №13»<country>Казахстан</country></aff><aff xml:lang="en">Municipal Policlinic №13<country>Kazakhstan</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru">ГКП на ПХВ «Городская поликлиника №2»<country>Казахстан</country></aff><aff xml:lang="en">Municipal Policlinic №2<country>Kazakhstan</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru">ГКП на ПХВ «Городская поликлиника №7»<country>Казахстан</country></aff><aff xml:lang="en">Municipal Policlinic №7<country>Kazakhstan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>11</day><month>10</month><year>2021</year></pub-date><volume>0</volume><issue>2</issue><fpage>61</fpage><lpage>67</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бисенова Н.М., Тулеубаева Э.А., Трофимчук Е.В., Ергалиева А.С., Таханова Р.Н., Айгожина Б.Х., Жидебаева К.К., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Бисенова Н.М., Тулеубаева Э.А., Трофимчук Е.В., Ергалиева А.С., Таханова Р.Н., Айгожина Б.Х., Жидебаева К.К.</copyright-holder><copyright-holder xml:lang="en">Bissenova N.M., Tuleubyeva Y.A., Trofimchuk Y.V., Yergsliyeva A.S., Takhanova R.N., Aigozhina B.H., Zhidebayeva K.K.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medecol.qmu.kz/jour/article/view/269">https://medecol.qmu.kz/jour/article/view/269</self-uri><abstract><p>Цель: изучение бактериальной структуры и уровня антибиотикочувствительности основных патогенов респираторного тракта взрослых амбулаторных пациентов. Материалы и методы: на базе микробиологической лаборатории АО «Национальный научный медицинский центр» проведено проспективное микробиологическое исследование микробного пейзажа и антибиотикочувствительности штаммов, выделенных из респираторного тракта 202 взрослых амбулаторных пациентов в период с сентября 2019 по октябрь 2020 г. Идентификация выделенных микроорганизмов осуществлялась на микробиологическом анализаторе «Vitek 2» (bioMerieux). Результаты и обсуждение: в исследование было включено 245 образцов клинического материала различной локализации. За исследуемый период из клинического материала было выделено 239 штаммов микроорганизмов. В мокроте и мазках из зева чаще других выделялся Streptococcus mitis (51,7% и 33,6% соответственно), в мазках из носа и уха - Staphylococcus aureus (32,5% и 31,3% соответственно). Заключение: результаты исследования показали, что у амбулаторных пациентов основным патогеном респираторного тракта являются штаммы Streptococcus mitis и Staphylococcus aureus. Стрептококки обладали высоким уровнем чувствительности к цефтриаксону (100%) и котримоксазолу (87,7%). Изоляты патогенного стафилококка обладали 100% чувствительностью к гентамицину и левофлоксацину, а также к котримоксазолу (96,2%).</p></abstract><trans-abstract xml:lang="en"><p>We aimed to study bacterial structure and antibiotic susceptibility of main pathogens of outpatients' respiretory tract. Materials and methods, a prospective microbiological study of bacterial landscape and antibiotic susceptibility of strains isolated from 202 outpatients' respiratory tract based on Microbiology Laboratory of National Scientific Medical Research Center during September 2019 to October 2020. Identification of isolates were performed by Vitek-2 automated system. Results and discussion: during study period, 245 clinical samples were included, 282 strains were isolated; of them and the most frequently isolated microorganisms from throat swabs and sputum was Streptococcus mitis (51.7% and 33.6%), from nasal and ear swabs - Staphylococcus aureus (32.5% and 31.3% respectively). Conclusion, based on our results the most frequently pathogens of outpatients' respiratory tract were St mitis with high level of susceptibility to ceftriaxone (100%), co-trimoxazole (87.7%) and S. aureus with susceptibility to gentamicin and levofloxacin (100%) and co-trimoxazole (96.2%).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>бактериальные инфекции</kwd><kwd>антибиотикочувствительность</kwd><kwd>респираторный тракт</kwd></kwd-group><kwd-group xml:lang="en"><kwd>bacterial infections</kwd><kwd>antibiotic susceptibility</kwd><kwd>respiratory tract</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Методические указания по стандартам микробиологических исследований в лаборатории клинической микробиологии. - Астана, 2008. - С. 11-12.</mixed-citation><mixed-citation xml:lang="en">Методические указания по стандартам микробиологических исследований в лаборатории клинической микробиологии. - Астана, 2008. - С. 11-12.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Свистушкин В. 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