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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medecol</journal-id><journal-title-group><journal-title xml:lang="ru">Медицина и экология</journal-title><trans-title-group xml:lang="en"><trans-title>Medicine and ecology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2305-6045</issn><issn pub-type="epub">2305-6053</issn><publisher><publisher-name>Карагандинский медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">medecol-255</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ТЕОРЕТИЧЕСКАЯ И ЭКСПЕРИМЕНТАЛЬНАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>THEORETICAL AND EXPERIMENTAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>ИЗОБРАЖЕНИЯ НЕВУСОВ КАК ДИАГНОСТИЧЕСКИЙ И ПРОГНОСТИЧЕСКИЙ ИНСТРУМЕНТЫ ПРИ ИЗУЧЕНИИ ПАТОЛОГИИ КОЖИ</article-title><trans-title-group xml:lang="en"><trans-title>REVIEW OF NEVI FOR MEDICAL EDUCATION USING DIGITAL PATHOLOGY TOOLS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ческа</surname><given-names>А.</given-names></name><name name-style="western" xml:lang="en"><surname>Chesca</surname><given-names>A. .</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сэндл</surname><given-names>Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Sandle</surname><given-names>T. .</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Абдулина</surname><given-names>Г. .</given-names></name><name name-style="western" xml:lang="en"><surname>Abdulina</surname><given-names>G. .</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">университет Трансильвании г. Брашов<country>Румыния</country></aff><aff xml:lang="en">Transilvania University of Brasov<country>Romania</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Университет Манчестера<country>Соединённые Штаты Америки</country></aff><aff xml:lang="en">Manchester University<country>United States</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru">Карагандинский медицинский университет<country>Казахстан</country></aff><aff xml:lang="en">Karaganda Medical University<country>Kazakhstan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>11</day><month>10</month><year>2021</year></pub-date><volume>0</volume><issue>1</issue><fpage>54</fpage><lpage>59</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ческа А..., Сэндл Т..., Абдулина Г..., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Ческа А., Сэндл Т., Абдулина Г...</copyright-holder><copyright-holder xml:lang="en">Chesca A..., Sandle T..., Abdulina G...</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medecol.qmu.kz/jour/article/view/255">https://medecol.qmu.kz/jour/article/view/255</self-uri><abstract><p>Цель исследования - использовать цифровые изображения невусов в качестве диагностического и прогностического инструмента для изучения патологии кожи. Исследования пигментных невусов привлекают внимание врачей тем, что они сигнализируют специализированной медицинской бригаде о возможном злокачественном перерождении. Образцы невусов были взяты из разных участков тела у детей в возрасте до 18 лет. Анализ пигментированных невусов проводится путем наблюдения за микроскопическими препаратами, обычно окрашенными гематоксилином с эозином, что позволяет проводить сравнительный анализ с прилегающими к невусу областями. Полученные данные могут включать в себя классификации по возрастным группам, полу, городским или сельским районам. Для повышения уровня медицинского образования получение цифровых изображений невусов может стать мощным средством обучения. Например, представляя данные студентам-медикам, можно привлечь внимание к типам травмированных невусов, которые могут переродиться в злокачественные новообразования.</p></abstract><trans-abstract xml:lang="en"><p>Studies on pigmented nevi (moles) attract medical attention by the fact that they signal to the specialized medical team possible malignant degeneration.. Nevi samples were taken from different areas of the body in children under the age of 18 years. The analysis of pigmented nevi is undertaken by observations on microscopic preparations, usually colored using the Hematoxylin &amp; Eosin stain (H&amp;E), which enables comparative analyzes to be made with the adjacent regions of the nevi. Collated data can include classifications by age groups, by sex, by urban or rural area. In order to advance medical education, capturing digital images of nevi can provide a powerful training tool. For example through the presentation of data to medical students it is possible to draw attention to the types of traumatized nevi that could possibly degenerate into malignancy.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>невусы</kwd><kwd>структура</kwd><kwd>анализ</kwd><kwd>наблюдения</kwd><kwd>особенности</kwd></kwd-group><kwd-group xml:lang="en"><kwd>nevi</kwd><kwd>structure</kwd><kwd>analysis</kwd><kwd>observations</kwd><kwd>particularities</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bae E. Demographics, Risk Factors, and Incidence of Melanoma in Patients in the New England VA Healthcare system /E. Bae, D. Leone, N. Konnikov //Mil. Med. - 2019. - V. 184 (5-6). -e408-e416.</mixed-citation><mixed-citation xml:lang="en">Bae E. Demographics, Risk Factors, and Incidence of Melanoma in Patients in the New England VA Healthcare system /E. Bae, D. Leone, N. Konnikov //Mil. Med. - 2019. - V. 184 (5-6). -e408-e416.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Bartos V. Malignant Melanomas of the Skin Arising on the Feet /V. Bartos, M. Kullova // Klin. Onkol. - 2018. - V. 31(4). - P. 289-292.</mixed-citation><mixed-citation xml:lang="en">Bartos V. Malignant Melanomas of the Skin Arising on the Feet /V. Bartos, M. Kullova // Klin. Onkol. - 2018. - V. 31(4). - P. 289-292.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Bristow I. Melanoma of the Foot /I. Bristow, C. Bower //Clin. Pediatr. Med. Surg. - 2016. - V. 33 (3). - P. 409-422.</mixed-citation><mixed-citation xml:lang="en">Bristow I. Melanoma of the Foot /I. Bristow, C. Bower //Clin. Pediatr. Med. Surg. - 2016. - V. 33 (3). - P. 409-422.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Bristow I. R.Clinical guidelines for the recognition of melanoma of the foot and nail unit / I. R. Bristow, D. A. de Berker, K. M. Acland //J. Foot. Ankle. Res. - 2010. - V. 3. - P. 25.</mixed-citation><mixed-citation xml:lang="en">Bristow I. R.Clinical guidelines for the recognition of melanoma of the foot and nail unit / I. R. Bristow, D. A. de Berker, K. M. Acland //J. Foot. Ankle. Res. - 2010. - V. 3. - P. 25.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Crompton J. G. Clinical implications of the eighth edition of the American Joint Committee on Cancer melanoma staging /J. G. Crompton, E. Gilbert, M. S. Brady //J. Surg. Oncol. - 2019. - V. 119(2). - P. 168-174.</mixed-citation><mixed-citation xml:lang="en">Crompton J. G. Clinical implications of the eighth edition of the American Joint Committee on Cancer melanoma staging /J. G. Crompton, E. Gilbert, M. S. Brady //J. Surg. Oncol. - 2019. - V. 119(2). - P. 168-174.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Hamm H. Congenital melanocytic nevi -a multifaceted problem, MMW /Fortschr. Med. -2007. - V. 149(6). - P. 33-35.</mixed-citation><mixed-citation xml:lang="en">Hamm H. Congenital melanocytic nevi -a multifaceted problem, MMW /Fortschr. Med. -2007. - V. 149(6). - P. 33-35.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Hoss D. M. Significant melanocytic lesions in infancy, childhood, and adolescence /D. M. Hoss, J. M. Grant-Kels /Dermatol. Clin. -1986. - V. 4(1). - P. 29-44.</mixed-citation><mixed-citation xml:lang="en">Hoss D. M. Significant melanocytic lesions in infancy, childhood, and adolescence /D. M. Hoss, J. M. Grant-Kels /Dermatol. Clin. -1986. - V. 4(1). - P. 29-44.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Jakobiec F. A. Relationship between Conjunctival Intraepithelial Dendritic Melanocytes and Nevocytes /F. A. Jakobiec, P. Cortes Barrantes, M. E. Aronow //Ocul. Oncol. Pathol. - 2020. - V. 6 (4). - P. 251-258.</mixed-citation><mixed-citation xml:lang="en">Jakobiec F. A. Relationship between Conjunctival Intraepithelial Dendritic Melanocytes and Nevocytes /F. A. Jakobiec, P. Cortes Barrantes, M. E. Aronow //Ocul. Oncol. Pathol. - 2020. - V. 6 (4). - P. 251-258.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Kovach R. Diagnosing and treating congenital melanocytic nevus simulating malignant melanoma /R. Kovach, J. Hochberg, M. Ardenghy //W. V. Med. J. - 1996. - V. 92 (4). - P. 191-193.</mixed-citation><mixed-citation xml:lang="en">Kovach R. Diagnosing and treating congenital melanocytic nevus simulating malignant melanoma /R. Kovach, J. Hochberg, M. Ardenghy //W. V. Med. J. - 1996. - V. 92 (4). - P. 191-193.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Krengel S. Current management approaches for congenital melanocytic nevi /S. Krengel, A. A. Marghoob //Dermatol. Clin. - 2012. - V. 30(3). - P. 377-387.</mixed-citation><mixed-citation xml:lang="en">Krengel S. Current management approaches for congenital melanocytic nevi /S. Krengel, A. A. Marghoob //Dermatol. Clin. - 2012. - V. 30(3). - P. 377-387.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Lallas A. The BRAAFF checklist: a new dermoscopic algorithm for diagnosing acral melanoma /A. Lallas, A. Kyrgidis, H. Koga //Br. J. Dermatol. - 2015. - V. 173(4). - P. 1041-1049.</mixed-citation><mixed-citation xml:lang="en">Lallas A. The BRAAFF checklist: a new dermoscopic algorithm for diagnosing acral melanoma /A. Lallas, A. Kyrgidis, H. Koga //Br. J. Dermatol. - 2015. - V. 173(4). - P. 1041-1049.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Lazova R. Spitz nevi and Spitzoid melanomas: exome sequencing and comparison with conventional melanocytic nevi and melanomas /R. Lazova, N. Pornputtapong, R. Halaban //Mod. Pathol. - 2017. - V. 30(5). - P. 640-649.</mixed-citation><mixed-citation xml:lang="en">Lazova R. Spitz nevi and Spitzoid melanomas: exome sequencing and comparison with conventional melanocytic nevi and melanomas /R. Lazova, N. Pornputtapong, R. Halaban //Mod. Pathol. - 2017. - V. 30(5). - P. 640-649.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Leech S. N. Neonatal giant congenital nevi with proliferative nodules: a clinicopathologic study and literature review of neonatal melanoma /S. N. Leech, H. Bell, N. Leonard //Arch. Dermatol. - 2004. - V. 140(1). - P. 83-88.</mixed-citation><mixed-citation xml:lang="en">Leech S. N. Neonatal giant congenital nevi with proliferative nodules: a clinicopathologic study and literature review of neonatal melanoma /S. N. Leech, H. Bell, N. Leonard //Arch. Dermatol. - 2004. - V. 140(1). - P. 83-88.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Nevares-Pomales O. W. Pigmented Lesions of the Nail Unit /O. W. Nevares-Pomales, C. J. Sarriera-Lazaro, Barrera-Llaurador //J. Am. J. Dermatopathol. - 2018. - V. 40(11). - P. 793-804.</mixed-citation><mixed-citation xml:lang="en">Nevares-Pomales O. W. Pigmented Lesions of the Nail Unit /O. W. Nevares-Pomales, C. J. Sarriera-Lazaro, Barrera-Llaurador //J. Am. J. Dermatopathol. - 2018. - V. 40(11). - P. 793-804.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Palicka G. A. Acral melanocytic nevi: prevalence and distribution of gross morphologic features in white and black adults /G. A. Palicka, A. R. Rhodes //Arch. Dermatol. - 2010. - V. 146 (10). - P. 1085-1094.</mixed-citation><mixed-citation xml:lang="en">Palicka G. A. Acral melanocytic nevi: prevalence and distribution of gross morphologic features in white and black adults /G. A. Palicka, A. R. Rhodes //Arch. Dermatol. - 2010. - V. 146 (10). - P. 1085-1094.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Richtig E. ASCO Congress 2018: melanoma treatment //Memo. - 2018. - V. 11(4). - P. 261-265.</mixed-citation><mixed-citation xml:lang="en">Richtig E. ASCO Congress 2018: melanoma treatment //Memo. - 2018. - V. 11(4). - P. 261-265.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Tannous Z. S. Congenital melanocytic nevi: clinical and histopathologic features, risk of melanoma, and clinical management /Z. S. Tannous, M. C. Mihm Jr., A. J. Sober //J. Am. Acad. Dermatol. - 2005. - V. 52(2). - P. 197-203.</mixed-citation><mixed-citation xml:lang="en">Tannous Z. S. Congenital melanocytic nevi: clinical and histopathologic features, risk of melanoma, and clinical management /Z. S. Tannous, M. C. Mihm Jr., A. J. Sober //J. Am. Acad. Dermatol. - 2005. - V. 52(2). - P. 197-203.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Wang B. Identification of the potential prognostic genes of human melanoma /B. Wang, X. L. Qu, Y. Chen /J. Cell. Physiol. - 2019. - V. 234(6). - P. 9810-9815.</mixed-citation><mixed-citation xml:lang="en">Wang B. Identification of the potential prognostic genes of human melanoma /B. Wang, X. L. Qu, Y. Chen /J. Cell. Physiol. - 2019. - V. 234(6). - P. 9810-9815.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Wang M. Surgical Management of Plantar Melanoma: A Retrospective Study in One Center /M. Wang, Y. Xu, J. Wang //J. Foot. Ankle. Surg. - 2018. - V. 57(4). - P. 689-693.</mixed-citation><mixed-citation xml:lang="en">Wang M. Surgical Management of Plantar Melanoma: A Retrospective Study in One Center /M. Wang, Y. Xu, J. Wang //J. Foot. Ankle. Surg. - 2018. - V. 57(4). - P. 689-693.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Wiesner T. Morphological and genetic aspects of Spitz tumors /T. Wiesner, H. Kutzner // Pathologe. - 2015. - V. 36(1). - P. 37-45.</mixed-citation><mixed-citation xml:lang="en">Wiesner T. Morphological and genetic aspects of Spitz tumors /T. Wiesner, H. Kutzner // Pathologe. - 2015. - V. 36(1). - P. 37-45.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
