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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medecol</journal-id><journal-title-group><journal-title xml:lang="ru">Медицина и экология</journal-title><trans-title-group xml:lang="en"><trans-title>Medicine and ecology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2305-6045</issn><issn pub-type="epub">2305-6053</issn><publisher><publisher-name>Карагандинский медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">medecol-240</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ТЕОРЕТИЧЕСКАЯ И ЭКСПЕРИМЕНТАЛЬНАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>THEORETICAL AND EXPERIMENTAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>МАКРОСКОПИЧЕСКИЕ МОРФОЛОГИЧЕСКИЕ ИЗМЕНЕНИЯ ПЛАЦЕНТЫ, АССОЦИИРУЮЩИЕСЯ С ПРЕЭКЛАМПСИЕЙ</article-title><trans-title-group xml:lang="en"><trans-title>MACROSCOPIC MORPHOLOGICAL CHANGES OF THE PLACENTA ASSOCIATED WITH PREECLAMPSIA</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мухаммад</surname><given-names>И. ..</given-names></name><name name-style="western" xml:lang="en"><surname>Mukhammad</surname><given-names>I. ..</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тусупбекова</surname><given-names>М. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Tussupbekova</surname><given-names>M. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Быкова</surname><given-names>Т. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Bykova</surname><given-names>T. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Камышанский</surname><given-names>Е. К.</given-names></name><name name-style="western" xml:lang="en"><surname>K Kamyshanskiy</surname><given-names>Ye. ..</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Костылева</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kostyieva</surname><given-names>O. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Журавлев</surname><given-names>С. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhuravlyov</surname><given-names>S. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Косицын</surname><given-names>Д. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Kositsyn</surname><given-names>D. L.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Некоммерческое акционерное общество «Медицинский университет Караганды»<country>Казахстан</country></aff><aff xml:lang="en">Non-profit joint-stock company «Karaganda medical university»<country>Kazakhstan</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Коммунальное государственное предприятие «Областная клиническая больница» Управления здравоохранения Карагандинской области<country>Казахстан</country></aff><aff xml:lang="en">Karaganda Regional Clinical Hospital<country>Kazakhstan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>07</day><month>09</month><year>2021</year></pub-date><volume>0</volume><issue>4</issue><fpage>107</fpage><lpage>115</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мухаммад И..., Тусупбекова М.М., Быкова Т.Н., Камышанский Е.К., Костылева О.А., Журавлев С.Н., Косицын Д.Л., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Мухаммад И..., Тусупбекова М.М., Быкова Т.Н., Камышанский Е.К., Костылева О.А., Журавлев С.Н., Косицын Д.Л.</copyright-holder><copyright-holder xml:lang="en">Mukhammad I..., Tussupbekova M.M., Bykova T.N., K Kamyshanskiy Y..., Kostyieva O.A., Zhuravlyov S.N., Kositsyn D.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medecol.qmu.kz/jour/article/view/240">https://medecol.qmu.kz/jour/article/view/240</self-uri><abstract><p>Цель работы: сравнительное изучение макроскопических характеристик плаценты от беременностей с преэклампсией и плаценты при физиологическом течении беременности. Материалы и методы: на основании данных о течении беременности и состоянии здоровья матери отобрано 355 плацент и разделено на 2 группы: от женщин, беременность которых протекала с преэклампсией, и от женщин с физиологическим течением беременности. Проанализированы макроскопические особенности плацент при преэклампсии. Результаты и выводы: преэклампсия связана с меньшим весом (379,0±78,9 против 439,0±53,1; p&lt;0,0001) и размером (8,3 (3,5-11,7) против 7,8 (5, 1-9,9) (p&lt;0,0001) плаценты, но с повышенным фетоплацентарным индексом 7,3 (3,5-11,7), извилистостью пуповины, отличной от нормы, а также сочетанными повреждениями пуповины, в том числе еще одним из структурных признаков пуповины, отличным от нормы (141 (76,6%) против 67 (45,0%) (p &lt;0,0001) по сравнению с плацентой от физиологической беременности.</p></abstract><trans-abstract xml:lang="en"><p>Objective: a comparative study of the macroscopic features of the placenta from pregnancies with preeclampsia and the placenta in the physiological course of pregnancy. Material and methods: based on the data on the course of pregnancy and the state of health of the mother, 355 placentas were selected in 2 groups: a group of pregnant women with preeclampsia and a group of pregnant women with a physiological course of pregnancy. The macroscopic features of the placenta in preeclampsia were analyzed. Results and conclusions: Preeclampsia is associated with lower weight (379.0±78.9 versus 439.0±53.1, (p&lt;0.0001) and height (8.3 (3.5-11.7) versus 7.8 (5,1-9.9) (p&lt;0.0001) of the placenta, but with an increased fetoplacental index of 7.3 (3.5-11.7), umbilical cord tortuosity other than normal, as well as combined cord injuries, including more one of the structural features of the umbilical cord, different from the norm (141 (76.6%) versus 67 (45.0%) (p&lt;0.0001) compared with placentas from physiological pregnancy.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>макроскопическая патология</kwd><kwd>плацента</kwd><kwd>преэклампсия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>macroscopic pathology</kwd><kwd>placenta</kwd><kwd>preeclampsia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Камышанский Е. К. 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