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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medecol</journal-id><journal-title-group><journal-title xml:lang="ru">Медицина и экология</journal-title><trans-title-group xml:lang="en"><trans-title>Medicine and ecology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2305-6045</issn><issn pub-type="epub">2305-6053</issn><publisher><publisher-name>Карагандинский медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">medecol-174</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LITERATURE REVIEWS</subject></subj-group></article-categories><title-group><article-title>ВЛИЯНИЕ ДИСФУНКЦИИ ЩИТОВИДНОЙ ЖЕЛЕЗЫ НА ОКСИДАНТНОЕ СОСТОЯНИЕ ОРГАНИЗМА</article-title><trans-title-group xml:lang="en"><trans-title>EFFECT OF THYROID DYSFUNCTION ON THE OXIDANT STATE OF THE ORGANISM</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Беков</surname><given-names>Е. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Bekov</surname><given-names>Ye. K.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Джакетаева</surname><given-names>Ш. Ж.</given-names></name><name name-style="western" xml:lang="en"><surname>Dzhaketayeva</surname><given-names>Sh. Zh.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аушева</surname><given-names>И. У.</given-names></name><name name-style="western" xml:lang="en"><surname>Ausheva</surname><given-names>I. U.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шинтаева</surname><given-names>Н. У.</given-names></name><name name-style="western" xml:lang="en"><surname>Shintayeva</surname><given-names>N. U.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Медицинский университет Караганды<country>Казахстан</country></aff><aff xml:lang="en">Karaganda medical university<country>Kazakhstan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>07</day><month>09</month><year>2021</year></pub-date><volume>0</volume><issue>2</issue><fpage>8</fpage><lpage>14</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Беков Е.К., Джакетаева Ш.Ж., Аушева И.У., Шинтаева Н.У., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Беков Е.К., Джакетаева Ш.Ж., Аушева И.У., Шинтаева Н.У.</copyright-holder><copyright-holder xml:lang="en">Bekov Y.K., Dzhaketayeva S.Z., Ausheva I.U., Shintayeva N.U.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medecol.qmu.kz/jour/article/view/174">https://medecol.qmu.kz/jour/article/view/174</self-uri><abstract><p>Целью проведенного исследования является ознакомление с проблемой патологии щитвоидной железы, которая остается чрезвычайно актуальной из-за высокой распространенности. Патология щитовидной железы проявляется дисфункцией (гипо-, гипер-, эутиреоидное) гормонов щитовидной железы, при которойнаблюдаются выраженные изменения метаболизма основного обмена, дисфункция окислидантного состояния организма.</p></abstract><trans-abstract xml:lang="en"><p>The objective of the article was to introduce the problem of thyroid pathology, which remains relevant due to the high prevalence. Pathology of the thyroid gland is manifested by dysfunction (hypo-, hyper-, euthyroid) of thyroid hormones, in which there are marked changes in the metabolism of the basal metabolism, dysfunction of the oxidative state of the organism.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>щитовидная железа</kwd><kwd>оксидантный статус</kwd><kwd>гормоны</kwd></kwd-group><kwd-group xml:lang="en"><kwd>thyroid</kwd><kwd>oxidative status</kwd><kwd>hormones</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Asayama K. Lipid peroxidation and free radical scavengers in thyroid dysfunction in the rat: a possible mechanism of injury to heart and skeletal muscle in hypothyroidism /K.Asayama, K.Dobashi, H.Hayashibe //Endocrinology. - 1987. - V. 121. - Pp. 2112-2118.</mixed-citation><mixed-citation xml:lang="en">Asayama K. 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