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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medecol</journal-id><journal-title-group><journal-title xml:lang="ru">Медицина и экология</journal-title><trans-title-group xml:lang="en"><trans-title>Medicine and ecology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2305-6045</issn><issn pub-type="epub">2305-6053</issn><publisher><publisher-name>Карагандинский медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">medecol-142</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LITERATURE REVIEWS</subject></subj-group></article-categories><title-group><article-title>К ВОПРОСУ ЭПИДЕМИОЛОГИИ РАССЕЯННОГО СКЛЕРОЗА</article-title><trans-title-group xml:lang="en"><trans-title>TO THE ISSUE OF MULTIPLE SCLEROSIS EPIDEMIOLOGY</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кульбаева</surname><given-names>З. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Kulbayeva</surname><given-names>Z. D.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Григолашвили</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Grigolashvili</surname><given-names>M. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Калиева</surname><given-names>Ш. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kaliyev</surname><given-names>S. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мясникова</surname><given-names>Ж. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Myasnikov</surname><given-names>Zh. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жасуланкызы</surname><given-names>А. ..</given-names></name><name name-style="western" xml:lang="en"><surname>Zhasulankyzy</surname><given-names>A. ..</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">НАО «Медицинский университет Караганды»<country>Казахстан</country></aff><aff xml:lang="en">NC JSC «Karaganda medical university»<country>Kazakhstan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>07</day><month>09</month><year>2021</year></pub-date><volume>0</volume><issue>4</issue><fpage>11</fpage><lpage>18</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кульбаева З.Д., Григолашвили М.А., Калиева Ш.С., Мясникова Ж.В., Жасуланкызы А..., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Кульбаева З.Д., Григолашвили М.А., Калиева Ш.С., Мясникова Ж.В., Жасуланкызы А...</copyright-holder><copyright-holder xml:lang="en">Kulbayeva Z.D., Grigolashvili M.A., Kaliyev S.S., Myasnikov Z.V., Zhasulankyzy A...</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medecol.qmu.kz/jour/article/view/142">https://medecol.qmu.kz/jour/article/view/142</self-uri><abstract><p>Авторами проведен подробный и критический анализ отечественной и зарубежной литературы по изучению уровня заболеваемости рассеянным склерозом, особенностям течения заболевания в различных этнических группах. Впервые заболевание было описано Шарко в 1868 г., после открытия контрастных веществ для микроскопирования исследование рассеянного склероза стало еще более активным и продуктивным. Однако на сегодняшний день вопросы этиологии и эпидемиологии остаются актуальными. В ходе многочисленных исследований было определено, что генетический фактор играет не последнюю роль в развитии рассеянного склероза. Вместе с тем у разных этнических групп при заболевании рассеянным склерозом отмечается разное количество генов, способствующих процессу. В настоящее отмечается тенденция к увеличению заболеваемости среди этнических групп, для которых ранее не был характерен рассеянный склероз, что способствовало активизации исследований в ряде стран.</p></abstract><trans-abstract xml:lang="en"><p>The authors carried out a detailed and critical analysis of domestic and foreign literature on the study of the incidence of multiple sclerosis, the characteristics of the disease course in various ethnic groups. At first the disease was described by Charcot in 1868 after the discovery of contrast agents for microscopy, the study of multiple sclerosis became even more active and productive. However, today the issues of etiology and epidemiology remain relevant. In the course of numerous studies, it was determined that the genetic factor plays an important role in the development of multiple sclerosis. At the same time, different ethnic groups with a disease of multiple sclerosis have a different number of genes that contribute to the process. Currently, there is a tendency to increase the incidence among ethnic groups for which multiple sclerosis was not previously characteristic, which contributed to the intensification of research in several countries.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>рассеянный склероз</kwd><kwd>эпидемиология</kwd><kwd>особенности течения рассеянного склероза</kwd></kwd-group><kwd-group xml:lang="en"><kwd>multiple sclerosis</kwd><kwd>epidemiology</kwd><kwd>features of the course of multiple sclerosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Абдрахманова М. Г. Клиническая и эпидемиологическая характеристика рассеянного склероза в Карагандинском регионе /М. Г. Абдрахманова, Р. А. Беляев, Н. В. Тарасова //Журн. неврологии и психиатрии. - 2015. - №2. - С. 5-7.</mixed-citation><mixed-citation xml:lang="en">Абдрахманова М. Г. 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