medecolМедицина и экологияMedicine and ecology2305-60452305-6053Карагандинский медицинский университетmedecol-141Research ArticleОБЗОРЫ ЛИТЕРАТУРЫLITERATURE REVIEWSИНТЕРМЕДИАТЫ КАТАБОЛИЗМА ПУРИНОВ ПРИ РАКЕ МОЛОЧНОЙ ЖЕЛЕЗЫPURINE CATABOLISM INTERMEDIATES IN BREAST CANCERЖумакаеваС. С.ZhumakayevaS. S.noemail@neicon.ruНАО «Медицинский университет Караганды»КазахстанNC JSC «Karaganda medical university»Kazakhstan20190709202104510Copyright © Жумакаева С.С., 20212021Жумакаева С.С.Zhumakayeva S.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://medecol.qmu.kz/jour/article/view/141

Заболеваемость раком молочной железы занимает второе место в общей структуре онкопатологии среди женщин и характеризуется ежегодным увеличением новых выявленных случаев. Одним из перспективных направлений является исследование роли пуриновых нуклеотидов и интермедиатов их катаболизма. В последнее время стали обсуждать взаимосвязь между метаболизмом пуринов и прогрессированием рака. Выдвигается предположение, что продукты катаболизма пуринов могут играть важную роль в развитии и прогрессировании онкопатологии.

The incidence of breast cancer is second in the overall structure of cancer pathology among women and is characterized by an annual increasing of new detected cases. One of the promising areas is the study of the role of purine nucleotides and intermediates of their catabolism. Recently, began to discuss the relationship between purine metabolism and cancer progression. It has been suggested that the products of catabolism of purines may play an important role in the development and progression of oncopathology.

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The authors declare that there are no conflicts of interest present.