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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medecol</journal-id><journal-title-group><journal-title xml:lang="ru">Медицина и экология</journal-title><trans-title-group xml:lang="en"><trans-title>Medicine and ecology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2305-6045</issn><issn pub-type="epub">2305-6053</issn><publisher><publisher-name>Карагандинский медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.59598/ME-2305-6053-2026-120-3-176-182</article-id><article-id custom-type="elpub" pub-id-type="custom">medecol-1370</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НАБЛЮДЕНИЯ ИЗ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASES</subject></subj-group></article-categories><title-group><article-title>Двустороннее уретероцеле с формированием крупного камня мочеточника</article-title><trans-title-group xml:lang="en"><trans-title>Clinical case of a bilateral ureterocele with formation of a large ureteral calculus</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пак</surname><given-names>Ю. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Pak</surname><given-names>Yu. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Z05K7M0, г. Астана, ул. Т. Рыскулова, 6</p></bio><bio xml:lang="en"><p>Z05K7M0, Astana c., T. Ryskulova str., 6</p></bio><email xlink:type="simple">office@astanaclinic.kz</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мухамеджанулы</surname><given-names>А.</given-names></name><name name-style="western" xml:lang="en"><surname>Mukhamedzhanuly</surname><given-names>A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Z05K7M0, г. Астана, ул. Т. Рыскулова, 6</p></bio><bio xml:lang="en"><p>Z05K7M0, Astana c., T. Ryskulova str., 6</p></bio><email xlink:type="simple">office@astanaclinic.kz</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бекмуратов</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Bekmuratov</surname><given-names>E. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Z05K7M0, г. Астана, ул. Т. Рыскулова, 6</p></bio><bio xml:lang="en"><p>Z05K7M0, Astana c., T. Ryskulova str., 6</p></bio><email xlink:type="simple">office@astanaclinic.kz</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бейсенов</surname><given-names>К. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Beisenov</surname><given-names>K. T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>010000, г. Астана, ул. Бейбитшилик, 49а</p></bio><bio xml:lang="en"><p>010000, Astana c., Beibitshilik str., 49a</p></bio><email xlink:type="simple">mail@amu.kz</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шарапатов</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sharapatov</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>010000, г. Астана, ул. Бейбитшилик, 49а</p></bio><bio xml:lang="en"><p>010000, Astana c., Beibitshilik str., 49a</p></bio><email xlink:type="simple">mail@amu.kz</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Абдихалиев</surname><given-names>Н. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Abdikhaliyev</surname><given-names>N. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Нурислам Еркалиевич Абдихалиев </p><p>010000, г. Астана, ул. Бейбитшилик, 49а</p></bio><bio xml:lang="en"><p>Nurislam Abdikhaliyev </p><p>010000, Astana c., Beibitshilik str., 49a</p></bio><email xlink:type="simple">abdi2000@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГКП на ПХВ «Городская многопрофильная больница №2»</institution><country>Казахстан</country></aff><aff xml:lang="en"><institution>SME on REM «Municipal multidisciplinary Hospital No. 2»</institution><country>Kazakhstan</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Кафедра урологии и андрологии, НАО «Медицинский университет Астана»</institution><country>Казахстан</country></aff><aff xml:lang="en"><institution>Department of Urology and Andrology, NC JSC «Astana Medical University</institution><country>Kazakhstan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>12</day><month>10</month><year>2026</year></pub-date><volume>0</volume><issue>3</issue><fpage>176</fpage><lpage>182</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Пак Ю.Г., Мухамеджанулы А., Бекмуратов Е.С., Бейсенов К.Т., Шарапатов Е.А., Абдихалиев Н.Е., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Пак Ю.Г., Мухамеджанулы А., Бекмуратов Е.С., Бейсенов К.Т., Шарапатов Е.А., Абдихалиев Н.Е.</copyright-holder><copyright-holder xml:lang="en">Pak Y.G., Mukhamedzhanuly A., Bekmuratov E.S., Beisenov K.T., Sharapatov E.A., Abdikhaliyev N.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medecol.qmu.kz/jour/article/view/1370">https://medecol.qmu.kz/jour/article/view/1370</self-uri><abstract><p>В современной урологической практике аномалии развития мочевыделительной системы, такие как уретероцеле, нередко становятся этиологическим фактором развития тяжелых форм мочекаменной болезни. Клинический случай 42-летней пациентки с двусторонним уретероцеле, осложненным крупным конкрементом мочеточника на фоне обструктивной уропатии, демонстрирует возможности современной малоинвазивной хирургии в лечении редких врожденных патологий у взрослых.</p><p>В 2025 г. в урологическом отделении ГКП на ПХВ «Городская многопрофильная больница №2» (г. Астана, Республика Казахстан) была успешно выполнена симультанная эндоскопическая операция: лазерная инцизия уретероцеле с обеих сторон в сочетании с контактной лазерной литотрипсией. Диагностический алгоритм, основанный на применении мультиспиральной компьютерной томографии, позволил детально верифицировать анатомические особенности порока и плотность конкремента. Несмотря на сложность симультанного вмешательства, операция характеризовалась минимальной инвазивностью и отсутствием интраоперационных осложнений. В послеоперационный период наблюдалась положительная динамика: достигнута полная деструкция камня, восстановлена адекватная уродинамика и стабилизирована функция почек (скорость клубочковой фильтрации 86-89 мл/мин/1,73 м2). Пациентка была выписана в удовлетворительном состоянии, что подтверждает высокую эффективность выбранной тактики.</p><p>Анализ приведенного случая из практики в контексте современной литературы показывает, что симультанные лазерные вмешательства позволяют существенно сократить сроки стационарного лечения, минимизировать анестезиологическую нагрузку и избежать этапности операций. Такой подход не только снижает риск развития ятрогенных осложнений, но и способствует скорейшей социально-трудовой реабилитации пациентов. Представленный клинический случай подчеркивает, что трансуретральная лазерная уретеротомия является безопасным, экономически оправданным и золотым стандартом лечения уретероцеле, обеспечивая надежную профилактику рецидивов обструкции и сохранение почечного резерва.</p></abstract><trans-abstract xml:lang="en"><p>In modern urological practice, anomalies of the urinary system development, such as ureterocele, often become an etiological factor for severe forms of urolithiasis. This clinical case of a 42-year-old female patient with bilateral ureterocele complicated by a large ureteral stone amidst obstructive uropathy demonstrates the capabilities of modern minimally invasive surgery in treating rare congenital pathologies in adults. In 2025, at the urological department of the SME on REM «Municipal multidisciplinary Hospital No. 2» (Astana c., Republic of Kazakhstan), a simultaneous endoscopic operation was successfully performed: bilateral laser ureterocele incision combined with contact laser lithotripsy.</p><p>The diagnostic algorithm, based on multispiral computed tomography, allowed for a detailed verification of the anatomical features of the malformation and the density of the calculus. Despite the complexity of the simultaneous intervention, the operation was characterized by minimal invasiveness and an absence of intraoperative complications. A positive clinical trend was observed in the postoperative period: complete stone destruction was achieved, adequate urodynamics were restored, and renal function was stabilized (glomerular filtration rate 86-89 mL/min/1.73 m²). The patient was discharged in satisfactory condition, confirming the high efficiency of the chosen strategy.</p><p>Analysis of this case within the context of current literature shows that simultaneous laser interventions significantly reduce the duration of inpatient treatment, minimize the anesthetic burden, and avoid staged surgeries. This approach not only reduces the risk of iatrogenic complications but also facilitates the rapid socio-occupational rehabilitation of patients. The presented clinical case emphasizes that transurethral laser ureterotomy is a safe, cost-effective, and gold standard treatment for ureterocele, providing reliable prevention of recurrent obstruction and preservation of the renal reserve.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>уретероцеле</kwd><kwd>мочекаменная болезнь</kwd><kwd>лазерная уретеротомия</kwd><kwd>контактная литотрипсия</kwd><kwd>клинический случай</kwd></kwd-group><kwd-group xml:lang="en"><kwd>ureterocele</kwd><kwd>urolithiasis</kwd><kwd>laser ureterotomy</kwd><kwd>contact lithotripsy</kwd><kwd>clinical case</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ghanem K., Leslie S.W., Badreldin A.M. Ureterocele. https://www.ncbi.nlm.nih.gov/books/NBK597362/</mixed-citation><mixed-citation xml:lang="en">Ghanem K., Leslie S.W., Badreldin A.M. 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