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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medecol</journal-id><journal-title-group><journal-title xml:lang="ru">Медицина и экология</journal-title><trans-title-group xml:lang="en"><trans-title>Medicine and ecology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2305-6045</issn><issn pub-type="epub">2305-6053</issn><publisher><publisher-name>Карагандинский медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.59598/ME-2305-6053-2026-118-1-110-119</article-id><article-id custom-type="elpub" pub-id-type="custom">medecol-1317</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>Современные аспекты клинического течения ветряной оспы у детей</article-title><trans-title-group xml:lang="en"><trans-title>Current aspects of the clinical course of varicella in children</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алшимбаева</surname><given-names>З. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Alshimbaeva</surname><given-names>Z. Ye.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зарина Ерсаиновна Алшимбаева</p><p>100008, г. Караганда, ул. Гоголя, 40</p></bio><bio xml:lang="en"><p>Zarina Yersainovna Alshimbaeva</p><p>100008, Karaganda, Gogolya str., 40</p></bio><email xlink:type="simple">zarya_995@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бегайдарова</surname><given-names>Р. Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Begaydarova</surname><given-names>R. Kh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>100008, г. Караганда, ул. Гоголя, 40</p></bio><bio xml:lang="en"><p>100008, Karaganda, Gogolya str., 40</p></bio><email xlink:type="simple">info@qmu.kz</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алшынбекова</surname><given-names>Г. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Alshynbekova</surname><given-names>G. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>100008, г. Караганда, ул. Гоголя, 40</p></bio><bio xml:lang="en"><p>100008, Karaganda, Gogolya str., 40</p></bio><email xlink:type="simple">info@qmu.kz</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дюсембаева</surname><given-names>А. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Dyusembaeva</surname><given-names>A. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>100008, г. Караганда, ул. Гоголя, 40</p></bio><bio xml:lang="en"><p>100008, Karaganda, Gogolya str., 40</p></bio><email xlink:type="simple">info@qmu.kz</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Золотарева</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zolotaryova</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>100008, г. Караганда, ул. Гоголя, 40</p></bio><bio xml:lang="en"><p>100008, Karaganda, Gogolya str., 40</p></bio><email xlink:type="simple">info@qmu.kz</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Омарова</surname><given-names>Г. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Omarova</surname><given-names>G. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>100008, г. Караганда, ул. Гоголя, 40</p></bio><bio xml:lang="en"><p>100008, Karaganda, Gogolya str., 40</p></bio><email xlink:type="simple">info@qmu.kz</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Кафедра инфекционных болезней и фтизиатрии НАО «Карагандинский медицинский университет»<country>Казахстан</country></aff><aff xml:lang="en">Department of Infectious Diseases and Phthisiology, Karaganda Medical University NC JSC<country>Kazakhstan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>05</day><month>07</month><year>2026</year></pub-date><volume>0</volume><issue>1</issue><fpage>110</fpage><lpage>119</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Алшимбаева З.Е., Бегайдарова Р.Х., Алшынбекова Г.К., Дюсембаева А.Е., Золотарева О.А., Омарова Г.М., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Алшимбаева З.Е., Бегайдарова Р.Х., Алшынбекова Г.К., Дюсембаева А.Е., Золотарева О.А., Омарова Г.М.</copyright-holder><copyright-holder xml:lang="en">Alshimbaeva Z.Y., Begaydarova R.K., Alshynbekova G.K., Dyusembaeva A.E., Zolotaryova O.A., Omarova G.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medecol.qmu.kz/jour/article/view/1317">https://medecol.qmu.kz/jour/article/view/1317</self-uri><abstract><p>В исследовании представлены результаты анализа клинического течения ветряной оспы у 221 детей, госпитализированных в Инфекционный центр КГП «Областная клиническая больница» Управления здравоохранения Карагандинской области за 2020-2024 гг.</p><p>В структуре госпитализированных больных с верифицированным диагнозом ветряной оспы преобладали дети в возрасте от 3 до 6 лет. Клиническая картина ветряной оспы характеризовалась развитием астеновегетативного синдрома у 58,8% пациентов, проявлявшегося слабостью, утомляемостью, головной болью и миалгией. Преморбидный фон более чем у половины наблюдаемых больных был отягощен различными заболеваниями, что способствовало развитию тяжелых осложнений в виде сепсиса (генерализованное системное воспаление) (3%), осложнений со стороны ЦНС (4%), осложнений со стороны дыхательной системы (37%), бактериальных инфекций со стороны кожных покровов (56%).</p><p>Необходимо широкое применение специфической профилактики в виде вакцинации. Вакцинация против ветряной оспы является эффективным методом профилактики и требует более широкого внедрения в педиатрическую практику.</p></abstract><trans-abstract xml:lang="en"><p>The study presents the results of the analysis of the clinical course of varicella in 221 children hospitalized in the Infection Center of the Regional Clinical Hospital of the Karaganda Region Health Department in 2020 – 2024.</p><p>The structure of hospitalized patients with the verified diagnosis of varicella was dominated by children aged 3 to 6 years. The clinical picture of varicella was characterized by the development of asthenic vegetative syndrome in 58.8% of patients, manifested by weakness, fatigue, headache and myalgia. The premorbid background in more than half of the observed patients was burdened by various diseases, which contributed to the development of severe complications in the form of sepsis (generalized systemic inflammation) (3%), complications from the central nervous system (4%), complications from the respiratory system (37%), bacterial infections from the skin (56%).</p><p>Widespread use of specific prevention in the form of vaccination is necessary. Vaccination against chickenpox is an effective method of prevention and requires wider implementation in pediatric practice.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>дети</kwd><kwd>ветряная оспа</kwd><kwd>осложнения</kwd><kwd>флегмона</kwd><kwd>лабораторные данные</kwd></kwd-group><kwd-group xml:lang="en"><kwd>children</kwd><kwd>chickenpox</kwd><kwd>complications</kwd><kwd>phlegmon</kwd><kwd>laboratory data</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Hussey H., Abdullahi L., Collins J. Varicella zos-ter virus-associated morbidity and mortality in Africa – a systematic review. BMC Infect. Dis. 2017; 17: 717. https://doi.org/10.1186/s12879-017-2815-9</mixed-citation><mixed-citation xml:lang="en">Hussey H., Abdullahi L., Collins J. Varicella zos-ter virus-associated morbidity and mortality in Africa – a systematic review. BMC Infect. 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