medecolМедицина и экологияMedicine and ecology2305-60452305-6053Карагандинский медицинский университетmedecol-125Research ArticleНАБЛЮДЕНИЯ ИЗ ПРАКТИКИCLINICAL CASESСИНДРОМ СВИТА У ПАЦИЕНТКИ С МИЕЛОДИСПЛАСТИЧЕСКИМ СИНДРОМОМSWEETS SYNDROME IN PATIENT WITH M YELODYSPLASTIC SYNDROMEТургуноваЛ. Г.TurgunovaL. G.noemail@neicon.ruКлодзинскийА. А.KlodzinskiA. A.noemail@neicon.ruБаймурзинаА. К.BaimurzinaA. K.noemail@neicon.ruЖауынбековаҚ. Н.ZhauynbekovaK. N.noemail@neicon.ruКарагандинский государственный медицинский университетКазахстанKaraganda medical universityKazakhstanТОО «Центр гематологии» г. КарагандыКазахстанLLP «Hematological center» of KaragandaKazakhstan201907092021028389Copyright © Тургунова Л.Г., Клодзинский А.А., Баймурзина А.К., Жауынбекова Қ.Н., 20212021Тургунова Л.Г., Клодзинский А.А., Баймурзина А.К., Жауынбекова Қ.Н.Turgunova L.G., Klodzinski A.A., Baimurzina A.K., Zhauynbekova K.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://medecol.qmu.kz/jour/article/view/125

В статье представлено описание клинического случая у пациентки 66 лет с миелодиспластическим синдромом, у которой развился синдром Свита. В литературе описаны различные ассоциации синдрома Свита у пациентов с миелодиспластическим синдромом, который мог развиться до или одновременно с ним. В данном клиническом случае у пациентки заболевание дебютировало синдромом Свита. Лечение синдрома Свита глюкокортикостероидами привело к регрессу проявлений. Диагностика и лечение синдрома Свита при миелодиспластическом синдроме имеет свои трудности, так как применение глюкокортикостероидов сопряжено с высоким риском развития инфекционных осложнений вследствие нарушения функции нейтрофилов, что и описано в клиническом случае.

In this article we describe clinical case of 66-year patient with myelodysplastic syndrome, which had developed the Sweet's syndrome. In literature were described various associations of Sweet syndrome in patients with myelodysplastic syndrome, which could develop before or simultaneously with disease. In this clinical case, the patient's disease debuted with Sweet's syndrome. Treatment of Sweet's syndrome with glucocorticosteroids led to regression of manifestations. Diagnosis and treatment of Sweet syndrome in myelodysplastic syndrome has some difficulties, because of using glucocorticosteroids is associated with a high risk of infectious complications due to impaired neutrophil function, as described in our clinical case.

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The authors declare that there are no conflicts of interest present.