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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medecol</journal-id><journal-title-group><journal-title xml:lang="ru">Медицина и экология</journal-title><trans-title-group xml:lang="en"><trans-title>Medicine and ecology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2305-6045</issn><issn pub-type="epub">2305-6053</issn><publisher><publisher-name>Карагандинский медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.59598/ME-2305-6053-2025-117-4-119-126</article-id><article-id custom-type="elpub" pub-id-type="custom">medecol-1157</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЭКОЛОГИЯ И ГИГИЕНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ECOLOGY AND HYGIENE</subject></subj-group></article-categories><title-group><article-title>Особенности заболеваемости острым холециститом в Акмолинской области: ретроспективный эпидемиологический анализ</article-title><trans-title-group xml:lang="en"><trans-title>Features of the incidence of acute cholecystitis in the Akmola region: a retrospective epidemiological analysis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Игісін</surname><given-names>Н. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Igissin</surname><given-names>N. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Нұрбек Сағынбекұлы Игісін</p><p>020000, г. Кокшетау, ул. Абая, 76;</p><p>010000, г. Астана, ул. Алматы, 13</p><p> </p></bio><bio xml:lang="en"><p>Nurbek Sagynbekuly Igissin</p><p>020000, Kokshetau c., Abai str., 76;</p><p>010000, Astana c., Almaty str., 13</p></bio><email xlink:type="simple">nurbek.igissin@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рүстемова</surname><given-names>К. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Rustemova</surname><given-names>K. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>020000, г. Кокшетау, ул. Абая, 76;</p><p>010000, г. Астана, ул. Алматы, 13</p></bio><bio xml:lang="en"><p>020000, Kokshetau c., Abai str., 76;</p><p>010000, Astana c., Almaty str., 13</p></bio><email xlink:type="simple">university@shokan.edu.kz</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аяғанов</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ayaganov</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра хирургических дисциплин</p><p>020000, г. Кокшетау, ул. Абая, 76</p></bio><bio xml:lang="en"><p>Department of Surgical Disciplines</p><p>020000,  Kokshetau c., Abai str., 76</p></bio><email xlink:type="simple">university@shokan.edu.kz</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Туребаев</surname><given-names>Д. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Turebayev</surname><given-names>D. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра хирургических болезней с курсами ангиохирургии и пластической хирургии</p><p>010000, г. Астана, ул. Алматы, 13;</p><p>010000, г. Астана, ул. Бейбітшілік, 49А</p></bio><bio xml:lang="en"><p>Department of General Surgery with Courses in Angiosurgery and Plastic Surgery</p><p>010000, Astana c., Almaty str., 13; </p><p>010000, Astana c., Beibitshilik str., 49A</p></bio><email xlink:type="simple">info@ca-informer.kz</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Билялова</surname><given-names>З. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Bilyalova</surname><given-names>Z. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>010000, г. Астана, ул. Алматы, 13</p></bio><bio xml:lang="en"><p>010000, Astana c., Almaty str., 13</p></bio><email xlink:type="simple">info@ca-informer.kz</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тельманова</surname><given-names>Ж. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Telmanova</surname><given-names>Zh. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>010000, г. Астана, ул. Алматы, 13</p></bio><bio xml:lang="en"><p>010000, Astana c., Almaty str., 13;</p></bio><email xlink:type="simple">nfo@ca-informer.kz</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Молдағали</surname><given-names>Р. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Moldagali</surname><given-names>R. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>010000, г. Астана, ул. Алматы, 13; </p><p>020000, г. Кокшетау, ул. Глинина, 54</p><p> </p></bio><bio xml:lang="en"><p>010000, Astana c., Almaty str., 13;</p><p>020000, Kokshetau c., Glinina str. 54</p></bio><email xlink:type="simple">info@ca-informer.kz</email><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шакеева</surname><given-names>А. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Shakeeva</surname><given-names>A. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра детской хирургии</p><p>010000, г. Астана, ул. Бейбітшілік, 49А</p></bio><bio xml:lang="en"><p>Department of Pediatric Surgery</p><p>010000, Astana c., Beibitshilik str. 49A</p></bio><email xlink:type="simple">rektorat@amu.kz</email><xref ref-type="aff" rid="aff-6"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шишкин</surname><given-names>И. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Shishkin</surname><given-names>I. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>010000,  г. Астана, ул. Алматы, 13; </p><p>020000, г. Кокшетау, ул. Абая, 76</p></bio><bio xml:lang="en"><p>010000, Astana c., Almaty str., 13;</p><p>020000, Kokshetau c., Abai str. 76</p></bio><email xlink:type="simple">info@ca-informer.kz</email><xref ref-type="aff" rid="aff-7"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Садритен</surname><given-names>А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sadriten</surname><given-names>A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>010000, г. Астана, ул. Бейбітшілік, 49А</p></bio><bio xml:lang="en"><p>010000, Astana c., Beibitshilik str. 49A</p></bio><email xlink:type="simple">rektorat@amu.kz</email><xref ref-type="aff" rid="aff-6"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Муратбекова</surname><given-names>С. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Muratbekova</surname><given-names>S. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>020000, г. Кокшетау, ул. Абая, 76</p></bio><bio xml:lang="en"><p>020000, Kokshetau c., Abai str. 76</p></bio><email xlink:type="simple">university@shokan.edu.kz</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дьяков</surname><given-names>С. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Dyakov</surname><given-names>S. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>010000, г. Астана, ул. Алматы, 13;</p><p>010000, г. Астана, проспект Абылай Хана, 15А</p></bio><bio xml:lang="en"><p>010000, Astana c., Almaty str., 13;</p><p>010000, Astana c., Abylaykhan ave. 15A</p></bio><email xlink:type="simple">info@ca-informer.kz</email><xref ref-type="aff" rid="aff-8"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Қожахмет</surname><given-names>К. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Kozhakhmet</surname><given-names>K. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>010000, г. Астана, ул. Алматы, 13;</p><p>020000, г. Кокшетау, ул. Абая, 76</p><p> </p></bio><bio xml:lang="en"><p>010000, Astana c., Almaty str., 13;</p><p>020000, Kokshetau c., Abai str. 76</p></bio><email xlink:type="simple">info@ca-informer.kz</email><xref ref-type="aff" rid="aff-7"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Исследовательский институт науки о жизни и здоровье, Высшая Школа медицины, НАО&#13;
«Кокшетауский университет им. Ш. Уалиханова»;ОО «Central Asian Institute for Medical Research»<country>Казахстан</country></aff><aff xml:lang="en">Research Institute of Life and Health Sciences, Higher School of Medicine, Sh. Ualikhanov Kokshetau University NС JSC; Central Asian Institute for Medical Research Public Association<country>Kazakhstan</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Высшая Школа медицины, НАО «Кокшетауский университет им. Ш. Уалиханова»<country>Казахстан</country></aff><aff xml:lang="en">Higher School of Medicine, Sh. Ualikhanov Kokshetau University NС JSC<country>Kazakhstan</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru">ОО «Central Asian Institute for Medical Research»; НАО «Медицинский университет Астана»<country>Казахстан</country></aff><aff xml:lang="en">Central Asian Institute for Medical Research Public Association; Astana Medical University NС JSC<country>Kazakhstan</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru">ОО «Central Asian Institute for Medical Research»<country>Казахстан</country></aff><aff xml:lang="en">Central Asian Institute for Medical Research Public Association<country>Kazakhstan</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru">ОО «Central Asian Institute for Medical Research»; Кокшетауский высший медицинский колледж<country>Казахстан</country></aff><aff xml:lang="en">Central Asian Institute for Medical Research Public Association; Kokshetau Higher Medical College<country>Kazakhstan</country></aff></aff-alternatives><aff-alternatives id="aff-6"><aff xml:lang="ru">НАО «Медицинский университет Астана»<country>Казахстан</country></aff><aff xml:lang="en">Astana Medical University NС JSC<country>Kazakhstan</country></aff></aff-alternatives><aff-alternatives id="aff-7"><aff xml:lang="ru">ОО «Central Asian Institute for Medical Research»; Высшая Школа медицины, НАО «Кокшетауский университет им. Ш. Уалиханова»<country>Казахстан</country></aff><aff xml:lang="en">Central Asian Institute for Medical Research Public Association; Higher School of Medicine, Sh. Ualikhanov Kokshetau University NС JSC<country>Kazakhstan</country></aff></aff-alternatives><aff-alternatives id="aff-8"><aff xml:lang="ru">ОО «Central Asian Institute for Medical Research»; Национальный научный центр травматологии и ортопедии им. акад. Н. Д. Батпенова МЗ РК<country>Казахстан</country></aff><aff xml:lang="en">Central Asian Institute for Medical Research Public Association; National Scientific Center of Traumatology and Orthopedics named after Academician N. D. Batpenov, Ministry of Health of the Republic of Kazakhstan<country>Kazakhstan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>22</day><month>01</month><year>2026</year></pub-date><volume>0</volume><issue>4</issue><fpage>119</fpage><lpage>126</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Игісін Н.С., Рүстемова К.Р., Аяғанов С.А., Туребаев Д.К., Билялова З.А., Тельманова Ж.Б., Молдағали Р.С., Шакеева А.Р., Шишкин И.Ю., Садритен А., Муратбекова С.К., Дьяков С.С., Қожахмет К.К., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Игісін Н.С., Рүстемова К.Р., Аяғанов С.А., Туребаев Д.К., Билялова З.А., Тельманова Ж.Б., Молдағали Р.С., Шакеева А.Р., Шишкин И.Ю., Садритен А., Муратбекова С.К., Дьяков С.С., Қожахмет К.К.</copyright-holder><copyright-holder xml:lang="en">Igissin N.S., Rustemova K.R., Ayaganov S.A., Turebayev D.K., Bilyalova Z.A., Telmanova Z.B., Moldagali R.S., Shakeeva A.R., Shishkin I.Y., Sadriten A., Muratbekova S.K., Dyakov S.S., Kozhakhmet K.K.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medecol.qmu.kz/jour/article/view/1157">https://medecol.qmu.kz/jour/article/view/1157</self-uri><abstract><sec><title>Цель</title><p>Цель. Анализ тенденций заболеваемости острым холециститом в Акмолинской области с 2009 по 2022 г.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Исследование основано на ретроспективном анализе данных МЗ РК по Международной классификации болезней 10 пересмотра (код К81). Для оценки динамики заболеваемости использовались методы статистики здравоохранения и анализа временных рядов.</p></sec><sec><title>Результаты и обсуждение</title><p>Результаты и обсуждение. В период 2009 – 2022 гг. в стационары Акмолинской области с диагнозом острый холецистит было госпитализировано 12 538 пациентов. Показатель стационарной заболеваемости снизился с 136,3±4,3 до 106,7±3,8 на 100 000 населения (p24 ч от начала симптомов) сократилась с 68,9 до 36,9 на 100 000 населения, что указывает на улучшение раннего обращения.</p></sec><sec><title>Выводы</title><p>Выводы. Исследование подчеркивает необходимость совершенствования медицинских подходов к лечению острого холецистита в Акмолинской области. Результаты указывают на решающую важность ранней диагностики и своевременной госпитализации для снижения осложнений. В настоящее время возникла необходимость в дополнительных исследованиях для пересмотра имеющихся и разработки более эффективных клинических протоколов.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To analyze the trends in the incidence of acute cholecystitis in the Akmola region from 2009 to 2022.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The study is based on a retrospective analysis of data from the Ministry of Health of the Republic of Kazakhstan using the International Classification of Diseases, 10th Revision (ICD10), code K81. To assess incidence dynamics, methods of health statistics and time series analysis were applied.</p></sec><sec><title>Results and discussion</title><p>Results and discussion. Between 2009 and 2022, a total of 12,538 patients were hospitalized with acute cholecystitis in the Akmola region. The hospital-based incidence rate decreased from 136.3±4.3 to 106.7±3.8 per 100,000 population (p24 hours after symptom onset) decreased from 68.9 to 36.9 per 100,000, reflecting improved early access to care.</p></sec><sec><title>Conclusions</title><p>Conclusions. The study highlights the need to improve medical approaches to the treatment of acute cholecystitis in the Akmola region. The results indicate the critical importance of early diagnosis and timely hospitalization to reduce complications. There is currently a need for additional research to review existing and develop more effective clinical protocols.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>острый холецистит</kwd><kwd>заболеваемость</kwd><kwd>госпитализация</kwd><kwd>хирургия</kwd><kwd>осложнения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>acute cholecystitis</kwd><kwd>morbidity</kwd><kwd>hospitalization</kwd><kwd>surgery</kwd><kwd>complications</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Гланц С. Медико-биологическая статистика. М.: Практика; 1998: 459.</mixed-citation><mixed-citation xml:lang="en">Glanc S. Mediko-biologicheskaja statistika. M.: Praktika; 1998: 459.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Мерков А.М., Поляков Л.Е. Санитарная статистика. 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